ArticleArchives of osteoporosis2024
Life's Essential 8 and osteoporosis in adults aged 50 years or older: data from the National Health and Nutrition Examination Survey.
Article in Archives of osteoporosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Response to comment on "association between the dietary index for gut microbiota and osteoporosis among middle-aged and older adults in the United States".Preventive medicine reports · 2025Article
- Adhering to Life's Essential 8 Is Associated With Greater Bone Mineral Accrual During Childhood and Adolescence.Journal of the American Heart Association · 2025Article
- Association between the dietary index for gut microbiota and osteoporosis among middle-aged and older adults in the United States.Preventive medicine reports · 2025Article
- Application of machine learning algorithms in osteoporosis analysis based on cardiovascular health assessed by life's essential 8: a cross-sectional study.Journal of health, population, and nutrition · 2025Article
- Association between life's essential 8 and bone mineral density among adults aged 20-59 years.Scientific reports · 2025Article
- Association between cardiovascular health and metabolic dysfunction-associated steatotic liver disease: a nationwide cross-sectional study.Journal of health, population, and nutrition · 2025Article
- Life's Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening.International journal of chronic obstructive pulmonary disease · 2025Article
- Association between cardiovascular health assessed by life's essential 8 and hyperuricemia in U.S. adults: the NHANES 2009-2020.Frontiers in endocrinology · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
In this cross-sectional study, we examined the association between Life's Essential 8 (LE8) and bone mineral density (BMD) as well as osteoporosis risk among adults aged 50 and over. The findings of this study revealed that higher LE8 scores were associated with higher BMD and reduced osteoporosis risk. PURPOSE: The objective of the present study was to evaluate the association between Life's Essential 8 (LE8) and bone mineral density (BMD), as well as osteoporosis risk, in adults aged 50 years or over.
methodsThis cross-sectional study recruited individuals who were 50 years old or older from the National Health and Nutrition Examination Survey. LE8 scores were evaluated and calculated according to the scoring algorithm based on the American Heart Association recommendations, which were further categorized into health behaviors (LE8-HB) and health factors (LE8-HF) scores. Furthermore, the present study utilized multivariate linear regression models to examine the correlations between BMD and LE8 scores. In addition, ordinal logistic regression models were employed to determine the associations between the risk of osteoporosis (normal BMD, osteopenia, and osteoporosis) and LE8 scores.
resultsThe final analysis included a total of 2910 participants, whose mean age was 64.49 ± 9.28 years. LE8 and LE8-HF scores exhibited a negative association with BMD and a positive association with osteoporosis risk in unadjusted models. Nevertheless, after adjustment for covariates, LE8 and LE8-HB scores exhibited a positive association with BMD and a negative association with osteoporosis risk, regardless of age, sex, or menopausal status.
conclusionsScoring systems based on multiple lifestyle and behavior factors, similar to LE8, have the potential to become a novel option and be used for osteoporosis risk assessment.
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Registered trials
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