ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024
Obesity increases the odds of intervertebral disc herniation and spinal stenosis; an MRI study of 1634 low back pain patients.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Summary of the best evidence for early mobilization after lumbar spinal fusion surgery: a systematic review.BMC surgery · 2025Pooled it
- One-year body mass index change and subsequent risk of lumbar disc herniation: a population-based cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Impact of GLP-1 Receptor Agonists on Chronic Low Back Pain in Patients with Obesity: A Prospective Pilot Cohort Study.medRxiv : the preprint server for health sciences · 2026Article
- Non-specific low back pain prevalence and associated factors among Chinese people aged 60 years and older: a cross-sectional study.Frontiers in public health · 2026Article
- Development and validation of a clinical predictive model for the risk of recurrence after unilateral biportal endoscopic diskectomy.Frontiers in surgery · 2026Article
- Lumbar Disc Herniation Resorption: When and How Does It Occur?Neurospine · 2026Review
- Construction and Validation of a Nomogram Prediction Model for Recurrent Lumbar Disc Herniation After Percutaneous Endoscopic Lumbar Discectomy.Risk management and healthcare policy · 2026Article
- Immunohistochemical analysis to detect a molecular signature in intervertebral disc degeneration.Histochemistry and cell biology · 2025Article
- Association between metabolism and low back pain: a cross-sectional study.Journal of orthopaedic surgery and research · 2025Article
- Redefining Surgical Boundaries for Obese Patients? Full Endoscopic Lumbar Discectomy Proves Equally Effective With Shorter Hospital Stay in Obese Patients.International journal of spine surgery · 2025Article
- Does body mass index influence intraoperative costs and operative times for open transforaminal lumbar interbody fusion? A time-driven activity-based costing analysis.North American Spine Society journal · 2025Article
- Global, regional, and national burden of low back pain for adults aged 55 and older 1990-2021: an analysis for the global burden of disease study 2021.BMC musculoskeletal disorders · 2025Article
- Associations between insulin resistance and low back pain risk in US adults: a cross-sectional study.Frontiers in medicine · 2025Article
- Evaluation of Clinical Symptoms of Unilateral S1 Nerve Injury Caused by Disc Herniation the via High Resolution MRI and DTI.Journal of pain research · 2025Article
- Cellular and molecular mechanisms underlying obesity in degenerative spine and joint diseases.Bone research · 2024Review
- Association of continuous BMI with health-related quality of life in the United States by age and sex.Obesity (Silver Spring, Md.) · 2024Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe objective of this study was to examine the relationships between BMI and intervertebral disc degeneration (DD), disc herniation (DH) and spinal stenosis (SS) using a large, prospectively recruited and heterogeneous patient population.
methodsPatients were recruited through the European Genodisc Study. An experienced radiologist scored MRI images for DD, DH and SS. Multivariate linear and logistic regression analyses were used to model the relationship between these variables and BMI with adjustment for patient and MRI confounders.
resultsWe analysed 1684 patients with a mean age of 51 years and BMI of 27.2 kg/m
conclusionsWhile an increase in BMI was associated with only a slight increase in DD, it was a stronger predictor for DH and SS, particularly in the upper lumbar discs, suggesting weight loss could be a useful strategy for helping prevent disorders associated with these pathologies.
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Registered trials
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