Evidence map›Paper›PMID 38363307›Full record

ArticleAnalytical and bioanalytical chemistry2024

Polyphenol exposure of mothers and infants assessed by LC-MS/MS based biomonitoring in breast milk.

Sabrina Berger, Ian Oesterle, Kolawole I Ayeni, Chibundu N Ezekiel, Annette Rompel, Benedikt Warth

Open access · hybridAbstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. The Functional Role of Polyphenols Across the Human Lifespan.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sabrina BergerDepartment of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria.ORCID http://orcid.org/0009-0005-8072-3149
Ian OesterleDepartment of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria.ORCID http://orcid.org/0000-0003-4106-5452
Kolawole I AyeniDepartment of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria.ORCID http://orcid.org/0000-0002-4849-5853
Chibundu N EzekielInstitute for Bioanalytics and Agro-Metabolomics, Department of Agrobiotechnology (IFA-Tulln), University of Natural Resources and Life Sciences Vienna (BOKU), Konrad-Lorenz Str. 20, 3430, Tulln, Austria.ORCID http://orcid.org/0000-0002-2113-2948
Annette RompelUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, 1090, Wien, Austria.ORCID http://orcid.org/0000-0002-5919-0553
Benedikt WarthDepartment of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria. benedikt.warth@univie.ac.at.ORCID http://orcid.org/0000-0002-6104-0706
University of Vienna · ATBOKU University · AT

Funding

Austrian Science Fund FWF P 32326
6 · The paper itself

Abstract

Exposure to polyphenols is relevant throughout critical windows of infant development, including the breastfeeding phase. However, the quantitative assessment of polyphenols in human breast milk has received limited attention so far, though polyphenols may positively influence infant health. Therefore, a targeted LC-MS/MS assay was developed to investigate 86 analytes representing different polyphenol classes in human breast milk. The sample preparation consisted of liquid extraction, salting out, freeze-out, and a dilution step. Overall, nearly 70% of the chemically diverse polyphenols fulfilled all strict validation criteria for full quantitative assessment. The remaining analytes did not fulfill all criteria at every concentration level, but can still provide useful semi-quantitative insights into nutritional and biomedical research questions. The limits of detection for all analyzed polyphenols were in the range of 0.0041-87 ng*mL

Indexed as

Milk, HumanPolyphenolsBiological MonitoringChromatography, LiquidFemaleGenisteinGlucuronidesHumansInfantLiquid Chromatography-Mass SpectrometryTandem Mass SpectrometryGenisteinGlucuronidesPolyphenolsBreast milkExposome researchHuman biomonitoringPolyphenolsTandem mass spectrometry

Identifiers

PMID38363307
PMCPMC10899372
OpenAlexW4391880945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.