Evidence map›Paper›PMID 38362914›Full record

ReviewEmerging topics in life sciences2024

Resisting death by metal: metabolism and Cu/Zn homeostasis in bacteria.

Matthew J Sullivan, Ignacio Terán, Kelvin G K Goh, Glen C Ulett

Open access · hybridAbstract readReview
In one paragraph

Review in Emerging topics in life sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Microbial metal physiology: ions to ecosystems.Nature reviews. Microbiology · 2025
    Review
  5. Review
  6. Article
  7. Regulatory Characterization of Two Cop Systems for Copper Resistance inInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Bacteria Under Metal Stress-Molecular Mechanisms of Metal Tolerance.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Matthew J SullivanSchool of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, U.K.ORCID 0000-0003-2276-3132
Ignacio TeránSchool of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, U.K.
Kelvin G K GohSchool of Pharmacy and Medical Sciences, and Menzies Health Institute Queensland, Griffith University, Gold Coast Campus, Gold Coast, QLD 4222, Australia.ORCID 0000-0001-8347-2043
Glen C UlettSchool of Pharmacy and Medical Sciences, and Menzies Health Institute Queensland, Griffith University, Gold Coast Campus, Gold Coast, QLD 4222, Australia.ORCID 0000-0002-9638-8091
Griffith University · AUUniversity of East Anglia · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal ions such as zinc and copper play important roles in host-microbe interactions and their availability can drastically affect the survival of pathogenic bacteria in a host niche. Mechanisms of metal homeostasis protect bacteria from starvation, or intoxication, defined as when metals are limiting, or in excess, respectively. In this mini-review, we summarise current knowledge on the mechanisms of resistance to metal stress in bacteria, focussing specifically on the homeostasis of cellular copper and zinc. This includes a summary of the factors that subvert metal stress in bacteria, which are independent of metal efflux systems, and commentary on the role of small molecules and metabolic systems as important mediators of metal resistance.

Indexed as

CopperMetalsBacteriaHomeostasisZincCopperMetalsZinccopperhomeostasismetabolismmetalsmall moleculeszinc

Identifiers

PMID38362914
PMCPMC10903455
OpenAlexW4391879355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.