ArticlePsychological medicine2024
The genetic epidemiology of schizotypal personality disorder.
Article in Psychological medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- The association between autism and psychosis and the tools used to measure it: An updated systematic review and meta-analysis.The British journal of clinical psychology · 2026Pooled it
- Childhood predictors of cluster A personality disorder traits in adolescence: a seven-wave birth cohort study.European child & adolescent psychiatry · 2026Article
- "Is a general belief in one's capabilities related to mental and physical health?": The relationships between self-efficacy, health outcomes, and health-related behaviour.BMC psychology · 2026Article
- Childhood Trauma Across the Schizophrenia Spectrum: A Comparison of Schizotypal Personality Disorder and Schizophrenia.Schizophrenia bulletin · 2026Article
- Neuro- and social-cognition in schizotypal personality disorder and schizophrenia: A spectrum of severity.Psychiatry research · 2025Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe concept of schizotypal personality disorder (SPD) emerged from observations of personality characteristics common in relatives of schizophrenic patients. While often studied in family designs, few studies and none with genetic measures, have examined SPD in epidemiological samples.
methodsWe studied individuals born in Sweden 1940-2000 with an ICD-10 diagnosis of SPD with no prior schizophrenia (SZ) diagnosis (
resultsSPD was rare, with a prevalence of 0.044%, and had high levels of comorbidity with autism spectrum disorder (ASD), OCD, ADHD, and major depression (MD), and increased rates of being single, unemployed and in receipt of welfare. Affected individuals had elevated levels of FGRS for SZ (+0.42), ASD (+0.30), MD (+0.29), and ADHD (+0.20). Compared to cases of schizophrenia, they had significantly lower rates of FGRS
conclusionsOur results not only support the designation of SPD as a schizophrenia spectrum disorder but also suggest potentially important etiologic links between SPD and ASD and, to a lesser extent, ADHD, OCD, and MD.
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