Evidence map›Paper›PMID 38362804›Full record

ArticleJournal of neurochemistry2024

Profiling amyloid-β peptides as biomarkers for cerebral amyloid angiopathy.

Emma van den Berg, Iris Kersten, Gunnar Brinkmalm, Kjell Johansson, Anna M de Kort, Catharina J M Klijn, Floris H B M Schreuder, Johan Gobom, Erik Stoops, Erik Portelius and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Observational
  6. Article
  7. Observational
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 5 countries.

Emma van den BergDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-9004-934X
Iris KerstenDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0009-0000-4964-8973
Gunnar BrinkmalmInstitute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.ORCID 0000-0001-6958-2393
Kjell JohanssonClinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.ORCID 0000-0003-0451-4669
Anna M de KortDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-5679-516X
Catharina J M KlijnDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-8495-4578
Floris H B M SchreuderDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-7815-0207
Johan GobomInstitute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.ORCID 0000-0001-6193-6193
Erik StoopsADx NeuroSciences, Ghent, Belgium.ORCID 0000-0001-9989-4486
Erik PorteliusClinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.ORCID 0000-0003-2708-7372
Eleni GkanatsiouInstitute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.ORCID 0000-0003-4443-2836
Henrik ZetterbergClinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.ORCID 0000-0003-3930-4354
Kaj BlennowInstitute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.ORCID 0000-0002-1890-4193
H Bea KuiperijDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-0635-7428
Marcel M VerbeekDepartment of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0003-4635-7876
Radboud University Nijmegen · NLSahlgrenska University Hospital · SEADx NeuroSciences · BEUniversity of Wisconsin–Madison · US

Funding

Cerebral amyloid angiopathy fluid biomarkers evaluation (CAFE)R01NS104147 · NINDS · UNIVERSITY OF RHODE ISLAND · PI VAN NOSTRAND, WILLIAM E. · 2018 to 2022
$3.2M
NIH HHS 5R01NS104147-02NINDS NIH HHS R01 NS104147The Galen and Hilary Weston Foundation NR170024ZonMw 733050822
6 · The paper itself

Abstract

Brain amyloid-β (Aβ) deposits are key pathological hallmarks of both cerebral amyloid angiopathy (CAA) and Alzheimer's disease (AD). Microvascular deposits in CAA mainly consist of the Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesBiomarkersCerebral Amyloid AngiopathyAgedAged, 80 and overFemaleHumansMaleMiddle AgedPeptide FragmentsAmyloid beta-PeptidesBiomarkersPeptide FragmentsAlzheimer's diseaseamyloid‐βbiomarkerscerebral amyloid angiopathycerebrospinal fluidmass spectrometry

Identifiers

PMID38362804
PMCPMC11260253
OpenAlexW4391882096

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.