Evidence map›Paper›PMID 38362687›Full record

ArticleCurrent medicinal chemistry2025

Does Gut Microbiome have an Effect on Wilson's Disease Phenotype?

Shan Gao, Mei Zhou, Hedong Zhang, Zhenchu Tang

Abstract read
PubMed Publisher
In one paragraph

Article in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shan GaoDepartment of Gastroenterology, the Second Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0003-1731-2249
Mei ZhouDepartment of Gastroenterology, the Second Xiangya Hospital, Central South University, Changsha, China.
Hedong ZhangClinical Research Center for Organ Transplantation in Hunan Province, Changsha, China.
Zhenchu TangHuman Key Laboratory of Tumor Models and Individualized Medicine, the Second Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0003-3869-7985
Central South University · CN

Funding

Changsha Municipal Natural Science Foundation kq2208320Research Project of the Hunan Health Committee B202303036518
6 · The paper itself

Abstract

Wilson's Disease (WD), a genetic metabolic disorder, is characterized by the accumulation of copper in the liver and brain, resulting in a range of clinical symptoms. The clinical manifestations of WD vary widely. The present study introduces the distinctive features of intestinal microbiota in Chinese patients with WD, presenting diverse clinical symptoms. It shows a reduction in the diversity of gut microbiota among patients with hepatic symptoms associated with WD, particularly in the genus responsible for SCFAs production. It demonstrates an increase in the

Indexed as

Gastrointestinal MicrobiomeHepatolenticular DegenerationAdolescentAdultCase-Control StudiesCopperFemaleHumansMaleMiddle AgedPhenotypeYoung AdultCopperantibioticsgut microbiomehormone.phenotypeprobioticsWilson’s disease

Identifiers

PMID38362687
OpenAlexW4391882102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.