Evidence map›Paper›PMID 38362408›Full record

ArticleChemical science2024

Modular, multi-robot integration of laboratories: an autonomous workflow for solid-state chemistry.

Amy M Lunt, Hatem Fakhruldeen, Gabriella Pizzuto, Louis Longley, Alexander White, Nicola Rankin, Rob Clowes, Ben Alston, Lucia Gigli, Graeme M Day and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 82 citations in OpenAlex.

  1. Review
  2. Article
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  6. Article
  7. Dara: Automated Multiple-Hypothesis Phase Identification and Refinement from Powder X‑ray Diffraction.Chemistry of materials : a publication of the American Chemical Society · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Accelerated Porosity Screening Using a Multichannel Colorimetric Array.Angewandte Chemie (International ed. in English) · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Amy M LuntDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.
Hatem FakhruldeenDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.
Gabriella PizzutoDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.ORCID https://orcid.org/0000-0002-8541-0759
Louis LongleyDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.
Alexander WhiteDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.
Nicola RankinDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.
Rob ClowesDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.
Ben AlstonDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.
Lucia GigliComputational Systems Chemistry, School of Chemistry, University of Southampton SO17 1BJ UK.ORCID https://orcid.org/0000-0003-1642-4898
Graeme M DayComputational Systems Chemistry, School of Chemistry, University of Southampton SO17 1BJ UK.ORCID https://orcid.org/0000-0001-8396-2771
Andrew I CooperDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.ORCID https://orcid.org/0000-0003-0201-1021
Samantha Y ChongDepartment of Chemistry and Materials Innovation Factory, University of Liverpool L7 3NY UK aicooper@liverpool.ac.uk schong@liverpool.ac.uk.ORCID https://orcid.org/0000-0002-3095-875X
University of Liverpool · GBUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Automation can transform productivity in research activities that use liquid handling, such as organic synthesis, but it has made less impact in materials laboratories, which require sample preparation steps and a range of solid-state characterization techniques. For example, powder X-ray diffraction (PXRD) is a key method in materials and pharmaceutical chemistry, but its end-to-end automation is challenging because it involves solid powder handling and sample processing. Here we present a fully autonomous solid-state workflow for PXRD experiments that can match or even surpass manual data quality, encompassing crystal growth, sample preparation, and automated data capture. The workflow involves 12 steps performed by a team of three multipurpose robots, illustrating the power of flexible, modular automation to integrate complex, multitask laboratories.

Identifiers

PMID38362408
PMCPMC10866346
OpenAlexW4390231999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.