Evidence map›Paper›PMID 38362367›Full record

ReviewClinical and experimental vaccine research2024

Immune modulation and possible pathological implications mediated by naturally produced immunoglobulin G idiotypes: from historical to recent experimental and clinical studies focused on atopic dermatitis.

Lucas Santander, Nicolle Rakanidis Machado, Beatriz Oliveira Fagundes, Jefferson Russo Victor

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical and experimental vaccine research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lucas SantanderMedical School, Santo Amaro University, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0002-7524-606X
Nicolle Rakanidis MachadoLaboratory of Medical Investigation LIM-56, Division of Dermatology, University of Sao Paulo, Medical School, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0002-8605-9104
Beatriz Oliveira FagundesLaboratory of Medical Investigation LIM-56, Division of Dermatology, University of Sao Paulo, Medical School, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0001-9628-9184
Jefferson Russo VictorLaboratory of Medical Investigation LIM-56, Division of Dermatology, University of Sao Paulo, Medical School, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0001-6092-8394
Universidade de São Paulo · BRUniversidade de Santo Amaro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the 1950s decade, it has been suggested that a naturally produced or induced repertoire of immunoglobulin G (IgG) idiotypes may exert some immunoregulatory functions. In the last decades, some more advanced theories have suggested that the repertoire of IgG idiotypes may influence the development or control of some atopic diseases. In atopic dermatitis (AD), some evidence indicated that the IgG repertoire obtained from these patients could effectively mediate regulatory functions on thymic and peripheral CD4+ and CD8+ T cells. Furthermore, some recent clinical trials have corroborated the hypothesis that IgG from AD patients can exert regulatory functions

Indexed as

Anti-idiotypic antibodiesAtopic dermatitisCD4+ TCD8+ TIdiotypesImmunoglobulin G

Identifiers

PMID38362367
PMCPMC10864882
OpenAlexW4392830448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.