Evidence map›Paper›PMID 38362213›Full record

ArticleFrontiers in public health2024

Social and biological evaluation of antimicrobial resistance (SOBEAR) in rural India: a study protocol.

Matrujyoti Pattnaik, Ashish Kumar Nayak, Sonam Karna, Tanveer Rehman, Subrat Kumar Sahoo, Subrata Kumar Palo, Srikanta Kanungo, Jaya Singh Kshatri, Debaprasad Parai, Kamini Walia and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Matrujyoti Pattnaik *Model Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Ashish Kumar Nayak *Model Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Sonam Karna *Model Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Tanveer RehmanModel Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Subrat Kumar SahooModel Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Subrata Kumar PaloModel Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Srikanta KanungoModel Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Jaya Singh KshatriModel Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Debaprasad ParaiModel Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Kamini WaliaDivision of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Sanghamitra PatiModel Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Debdutta BhattacharyaModel Rural Health Research Unit, ICMR-Regional Medical Research Centre, Cuttack, India.
Regional Medical Research Centre · INIndian Council of Medical Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial resistance (AMR) has been one of the biggest global health threats in recent years, mostly in low- and middle-income countries, which requires urgent research using a multidisciplinary research approach. The use of large quantities of antimicrobial drugs inappropriately for humans, poultry and agriculture has been recognized as a leading cause of antibiotic resistance and the predominance of drug-resistance pathogens in the environment. This protocol aims to describe the use/misuse of antibiotics (ABs) in the community and evaluate clinical samples from healthcare settings to detect genes associated with antimicrobial resistance. Methods: We will conduct a community-level survey in different villages of the Tigiria block to assess knowledge and awareness on ABs and AMR. We will conduct in-depth interviews (IDIs) with doctors, pharmacists, nurses and drug sellers, as well as focus group discussions (FGDs) with ASHA and ANM workers who are involved in antibiotic supplies to the community. Quantitative data from the community survey and qualitative data of IDIs and FGDs will be linked and analyzed using statistical modeling and iterative thematic content analysis. Specimens (stool, urine, blood and wound/pus) will be collected from clinically diagnosed patients of different healthcare centers of Tigiria block. The samples will be cultured for bacterial isolation and antibiotic sensitivity testing. Genomic DNA will be isolated from positive bacterial cultures and sequenced using PCR to evaluate high-threat multi-drug resistance organisms (MDROs), screening of plasmid-mediated quinolone resistance (PMQR) genes, antimicrobial genes responsible for MDR and quinolone resistance-determining regions (QRDRs). Conclusion: This is the community-based protocol to evaluate the knowledge, attitudes, awareness and practices regarding ABs and AMR. The study protocol establishes a foundation for evaluating population-based prevalence and risk factors for AMR and MDROs in rural areas of the Odisha state, India.

Indexed as

Anti-Bacterial AgentsQuinolonesDrug Resistance, BacterialHealth Knowledge, Attitudes, PracticeHumansIndiaQualitative ResearchAnti-Bacterial AgentsQuinolonesAMRantibioticsbiologicalprotocolsocial

Identifiers

PMID38362213
PMCPMC10867149
OpenAlexW4391445476

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.