Evidence map›Paper›PMID 38362152›Full record

ArticleFrontiers in pharmacology2024

Determination of glomerular filtration rate "en passant" after high doses of iohexol for computed tomography in intensive care medicine-a proof of concept.

Alexander Dejaco, Christoph Dorn, Michael Paal, Michael Gruber, Bernhard M Graf, Martin G Kees

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alexander DejacoDepartment of Anesthesia, University Hospital Regensburg, Regensburg, Germany.
Christoph DornInstitute of Pharmacy, University of Regensburg, Regensburg, Germany.
Michael PaalInstitute for Laboratory Medicine, Hospital of the University of Munich (LMU), Munich, Germany.
Michael GruberDepartment of Anesthesia, University Hospital Regensburg, Regensburg, Germany.
Bernhard M GrafDepartment of Anesthesia, University Hospital Regensburg, Regensburg, Germany.
Martin G KeesDepartment of Anesthesia, University Hospital Regensburg, Regensburg, Germany.
University Hospital Regensburg · DELudwig-Maximilians-Universität München · DEUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate assessment of renal function is of great clinical and scientific importance, as it is an important pharmacokinetic covariate of pivotal drugs. The iohexol clearance is nearly identical to the glomerular filtration rate, but its determination usually requires an intravenous injection and therefore bears intrinsic risks. This motivates to showcase an

Indexed as

contrast-enhanced computed tomography imaging“en passant” iohexol clearanceestimated glomerular filtration rate (eGFR)intensive care medicine (ICM)measured glomerular filtration rate (mGFR)pharmacokinetic studies

Identifiers

PMID38362152
PMCPMC10867190
OpenAlexW4391445728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.