Evidence map›Paper›PMID 38362096›Full record

ArticleSaudi journal of medicine & medical sciences

Spectrum of Organic Aciduria Diseases in Tunisia: A 35-year Retrospective Study.

Awatef Jelassi, Fahmi Nasrallah, Emna Talbi, Mohamed Bassem Hammami, Rihab Ghodbane, Haifa Sanhaji, Moncef Feki, Naziha Kaabachi, Sameh Hadj-Taieb

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of medicine & medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Awatef JelassiDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Fahmi NasrallahDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Emna TalbiDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Mohamed Bassem HammamiDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Rihab GhodbaneDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Haifa SanhajiDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Moncef FekiDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Naziha KaabachiDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Sameh Hadj-TaiebDepartment of Clinical Chemistry, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.
Tunis El Manar University · TNTunis University · TNFaculté de médecine de TunisHôpital La Rabta · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Organic aciduria diseases (OADs) occur worldwide, with differences in prevalence and patterns between populations. Objectives: To describe the spectrum of OADs identified in Tunisia over a 35-years period. Materials and Methods: This retrospective study included patients who were diagnosed with OADs between 1987 and 2022 in the Laboratory of Biochemistry, Rabta Hospital, Tunisia. Organic acids were analyzed using gas chromatography-mass spectrometry. Results: A total of 30,670 urine samples were analyzed for OADs, of which 471 were positive for OADs. The estimated incidence of OADs in Tunisia was 6.78 per 100,000 live births. Methylmalonic ( Conclusions: In Tunisia, OADs are relatively frequent, but there are shortcomings regarding the diagnosis of these disorders. The frequency and health/social impact of these disorders warrant the need for implementing newborn screening programs and suitable patient management.

Indexed as

diagnosisepidemiologyinborn errors metabolismIncidenceinherited errors of amino acid metabolismorganic aciduriasTunisia

Identifiers

PMID38362096
PMCPMC10866378
OpenAlexW4391018063

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.