Evidence map›Paper›PMID 38361937›Full record

ArticleFrontiers in immunology2024

Dietary docosahexaenoic acid supplementation inhibits acute pulmonary transcriptional and autoantibody responses to a single crystalline silica exposure in lupus-prone mice.

Preeti S Chauhan, Abby D Benninghoff, Olivia K Favor, James G Wagner, Ryan P Lewandowski, Lichchavi D Rajasinghe, Quan-Zhen Li, Jack R Harkema, James J Pestka

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Preeti S Chauhan *Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Abby D Benninghoff *Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, United States.
Olivia K FavorInstitute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
James G WagnerInstitute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Ryan P LewandowskiDepartment of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI, United States.
Lichchavi D RajasingheDepartment of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States.
Quan-Zhen LiGenecopoeia Inc, Rockville, MD, United States.
Jack R HarkemaDepartment of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, United States.
James J PestkaInstitute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Michigan State University · USUtah State University · USGeneCopoeia (United States) · US

Funding

Role of alveolar macrophage in omega-3 fatty acid amelioration of silica-triggered autoimmunity.R01ES027353 · NIEHS · MICHIGAN STATE UNIVERSITY · PI Andrew Olive · 2017 to 2026
$4.8M
Integrative Pharmacological Sciences Training Program (IPSTP)T32GM142521 · NIGMS · MICHIGAN STATE UNIVERSITY · PI ANNE M. DORRANCE, Gina Marie Leinninger · 2021 to 2026
$2.4M
NIEHS NIH HHS R01 ES027353NIGMS NIH HHS T32 GM142521
6 · The paper itself

Abstract

Introduction: Workplace exposure to respirable crystalline silica (cSiO Methods: This study aimed to test the hypothesis that dietary DHA supplementation impacts acute transcriptional and autoantibody responses in the lungs of female NZBWF1 mice 1 and 4 wk after a single high-dose cSiO Results: DHA partially alleviated cSiO Discussion: Taken together, DHA mitigated cSiO

Indexed as

Docosahexaenoic AcidsLungAnimalsAutoantibodiesChemokinesCytokinesDietary SupplementsFemaleHumansInflammationMiceSilicon DioxideAutoantibodiesChemokinesCytokinesDocosahexaenoic AcidsSilicon Dioxideautoantibodyautoimmune diseasecrystalline silicadocosahexaenoic acid (DHA)inflammationlung pathologyomega-3 fatty acidsystemic lupus erythematosus

Identifiers

PMID38361937
PMCPMC10867581
OpenAlexW4391440997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.