ArticleFrontiers in neurology2024
Analysis of etiology and clinical features of spontaneous downbeat nystagmus: a retrospective study.
Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 9 citations in OpenAlex.
- High-frequency vestibulo-ocular reflex (VOR) evaluation in patients with spontaneous downbeat nystagmus: a case-control study.Journal of neurology · 2026Article
- Vestibular deficit and recovery in rare forms of benign paroxysmal positional vertigo with downbeat nystagmus.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Gravity-Dependent Modulation of Downbeat Nystagmus: Insights From Velocity-Storage Dysfunction.Annals of clinical and translational neurology · 2026Article
- Vestibular migraine. Clinical and diagnostic challenges, and emerging therapeutic approaches.Current opinion in neurology · 2026Review
- Multi-sequence MRI signal intensity ratios as candidate imaging correlates for audiovestibular dysfunction in vestibular schwannoma.Frontiers in neurology · 2026Observational
- Downbeat Nystagmus: Case Report, Updated Review, Therapeutics, and Neurorehabilitation.Brain sciences · 2025Article
- Clinical spectrum of positional downbeat nystagmus: a diagnostic approach.Journal of neurology · 2025Review
- Linking Downbeat Nystagmus and Aquaporin-4-Positive Neuromyelitis Optica: A Closer Look at Their Hidden Relationship.Cureus · 2024Article
- Downbeat nystagmus: a clinical and pathophysiological review.Frontiers in neurology · 2024Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the topical diagnosis, possible etiology and mechanism of spontaneous downbeat nystagmus (sDBN) patients with dizziness/vertigo. Methods: The clinical features of dizziness/vertigo patients accompanied with DBN were retrospectively reviewed in the Vertigo Center of our hospital from January 2018 to March 2021. The clinical features of dizziness/vertigo patients accompanied with DBN were reviewed. Comprehensive VNG, bithermal caloric testing, video-head-impulse test (vHIT), vestibular-evoked myogenic potentials (VEMP), head magnetic resonance imaging (MRI), three-dimensional fluid-attenuated incersion recovery magnetic resonance imaging (3D-FLAIR MRI) in the inner ear, serum immunology and other examinations were to determine the lesion site, and analyze its possible etiology and mechanism. Results: A total of 54 patients were included. Among them, 70.4% ( Conclusion: In our study, DBN patients have a relative decrease in posterior semicircular canal gain, which is possibly a particular result found in a subset of downbeat nystagmus patients. The changes in nystagmus during positional testing may be helpful in distinguishing between peripheral and central causes.
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