Evidence map›Paper›PMID 38361002›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Safety of bubble nasal intermittent positive pressure ventilation (NIPPV) versus bubble nasal continuous positive airway pressure (NCPAP) in preterm infants with respiratory distress.

Stephen C John, Mehak Garg, Mounika Muttineni, Ann M Brearley, Praveen Rao, Vineet Bhandari, Tina Slusher, Srinivas Murki

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06697951 (Feasibility of Using Bubble Nasal Intermittent Pressure Ventilation Using the Neovent in Low-resource Settings), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06697951 narecruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility of Using Bubble Nasal Intermittent Pressure Ventilation Using the Neovent in Low-resource Settings

TypeinterventionalSponsorTina SlusherRan2025 to 2025Enrolled70ConditionsRespiratory Distress of NewbornArmsbilevel ventilation with the Neovent
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Bubble NIPPV: Guidelines for Use.Children (Basel, Switzerland) · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Stephen C John *Department of Medicine-Pediatrics, University of Minnesota, Minneapolis, MN, USA. scjres@gmail.com.ORCID 0000-0002-8129-4180
Mehak Garg *Department of Neonatology, Paramitha Women and Children's Hospital, Hyderabad, India.
Mounika MuttineniDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Ann M BrearleyDivision of Biostatistics and Health Data Science, University of Minnesota, Minneapolis, MN, USA.
Praveen RaoDepartment of Neonatology, Paramitha Women and Children's Hospital, Hyderabad, India.ORCID 0000-0003-1175-2286
Vineet BhandariDivision of Neonatology, Department of Pediatrics, The Children's Regional Hospital at Cooper/Cooper Medical School of Rowan University, Camden, NJ, USA.ORCID 0000-0002-4900-6636
Tina SlusherDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Srinivas MurkiDepartment of Neonatology, Paramitha Women and Children's Hospital, Hyderabad, India.
University of Minnesota · USNiloufer Hospital · INCooper Medical School of Rowan University · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
NCATS NIH HHS UL1 TR002494U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (NCATS) ULI-TR002494
6 · The paper itself

Abstract

objectiveNasal Intermittent Positive Pressure Ventilation (NIPPV) is an effective therapy for infants in respiratory distress. We here report the safety of a novel, low-cost, non-electric bubble NIPPV device in comparison with bubble NCPAP. STUDY

designAt Paramitha Children's Hospital (Hyderabad, India), preterm (n = 60) neonates with moderate respiratory distress were pragmatically allocated to bubble NCPAP (5-8 cm H

resultsOne patient in each arm developed minor nasal septal injury (grade 3 on NCPAP, grade 2 on NIPPV); no patients in either arm developed a clinically significant pneumothorax or abdominal distention.

conclusionThe similar rates of nasal septal injury, pneumothorax and abdominal distention suggest that bubble NIPPV has a similar safety profile as bubble NCPAP for preterm infants in respiratory distress.

Indexed as

Continuous Positive Airway PressureInfant, PrematureIntermittent Positive-Pressure VentilationRespiratory Distress Syndrome, NewbornFemaleHumansIndiaInfant, NewbornMaleNasal SeptumPneumothorax

Identifiers

PMID38361002
OpenAlexW4391847407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.