Evidence map›Paper›PMID 38360921›Full record

ReviewPediatric cardiology2024

Right Ventricular and Outflow Tract Functional Characteristics After Repair of Tetralogy of Fallot with Major Aortopulmonary Collaterals.

Zsofia B Long, Rajesh Punn, Yulin Zhang, Alisa A Arunamata, Ritu Asija, Michael Ma, Frank L Hanley, Doff B McElhinney

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zsofia B LongDepartment of Pediatrics, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA. zlong@stanford.edu.
Rajesh PunnDepartment of Pediatrics, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Yulin ZhangClinical and Translational Research Program, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Alisa A ArunamataDepartment of Pediatrics, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Ritu AsijaDepartment of Pediatrics, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Michael MaDepartment of Cardiothoracic Surgery, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Frank L HanleyDepartment of Cardiothoracic Surgery, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Doff B McElhinneyDepartment of Pediatrics, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Stanford University · USLucile Packard Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes right ventricle (RV) characteristics and right ventricle to pulmonary artery (RV-PA) conduit function pre- and post-repair in patients with tetraology of Fallot with major aortopulmonary collaterals (TOF/MAPCAs). We reviewed patients who underwent single-stage, complete unifocalization, and repair of TOF/MAPCAs between 2006 and 2019 with available pre- and early postoperative echocardiograms. For a subset of patients, 6-12 month follow-up echocardiogram was available. RV and left ventricle (LV) characteristics and RV-PA conduit function were reviewed. Wilcoxon signed rank test and McNemar's test were used. 170 patients were reviewed, 46 had follow-up echocardiograms. Tricuspid valve annular plane systolic excursion (TAPSE) Z-scores were reduced from pre- (Z-score 0.01) to post-repair (Z-score -4.5, p < 0.001), improved but remained abnormal at follow-up (Z-score -4.0, p < 0.001). RV fractional area change (FAC) and LV ejection fraction were not significantly different before and after surgery. Conduit regurgitation was moderate or greater in 11% at discharge, increased to 65% at follow-up. RV-PA conduit failure (severe pulmonary stenosis or severe pulmonary regurgitation) was noted in 61, and 63% had dilated RV (diastolic RV area Z-score > 2) at follow-up. RV dilation correlated with the severe conduit regurgitation (p = 0.018). Longitudinal RV function was reduced after complete repair of TOF/MAPCAs, with decreased TAPSE and preserved FAC and LV ejection fraction. TAPSE improved but did not normalize at follow-up. Severe RV-PA conduit dysfunction was observed prior to discharge in 11% of patients and in 61% at follow-up. RV dilation was common at follow-up, especially in the presence of severe conduit regurgitation.

Indexed as

Cardiac Surgical ProceduresHeart FailurePulmonary Valve StenosisTetralogy of FallotHeart VentriclesHumansRetrospective StudiesVentricular Function, RightRight ventricleRight ventricle to pulmonary artery conduitTetralogy of Fallot with major aortopulmonary collateralsTricuspid valve annular plane systolic excursion

Identifiers

PMID38360921
OpenAlexW4391880188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.