Evidence map›Paper›PMID 38360720›Full record

ArticleBioData mining2024

m1A-Ensem: accurate identification of 1-methyladenosine sites through ensemble models.

Muhammad Taseer Suleman, Fahad Alturise, Tamim Alkhalifah, Yaser Daanial Khan

Abstract read
In one paragraph

Article in BioData mining, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad Taseer SulemanDepartment of Computer Science, School of Systems and Technology, University of Management and Technology, Lahore, 54770, Pakistan.
Fahad AlturiseDepartment of Computer, College of Science and Arts in Ar Rass, Qassim University, Ar Rass, Qassim, Saudi Arabia. falturise@qu.edu.sa.
Tamim AlkhalifahDepartment of Computer, College of Science and Arts in Ar Rass, Qassim University, Ar Rass, Qassim, Saudi Arabia.
Yaser Daanial KhanDepartment of Computer Science, School of Systems and Technology, University of Management and Technology, Lahore, 54770, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background1-methyladenosine (m1A) is a variant of methyladenosine that holds a methyl substituent in the 1st position having a prominent role in RNA stability and human metabolites.

objectiveTraditional approaches, such as mass spectrometry and site-directed mutagenesis, proved to be time-consuming and complicated. METHODOLOGY: The present research focused on the identification of m1A sites within RNA sequences using novel feature development mechanisms. The obtained features were used to train the ensemble models, including blending, boosting, and bagging. Independent testing and k-fold cross validation were then performed on the trained ensemble models.

resultsThe proposed model outperformed the preexisting predictors and revealed optimized scores based on major accuracy metrics.

conclusionFor research purpose, a user-friendly webserver of the proposed model can be accessed through https://taseersuleman-m1a-ensem1.streamlit.app/ .

Indexed as

Artificial IntelligenceComputational BiologyComputational ModelDecision TreesGeneticsNucleotide SequenceRespiratory DiseaseRNASequence AnalysisStatistical Model

Identifiers

PMID38360720
PMCPMC10868122

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.