Evidence map›Paper›PMID 38360715›Full record

ArticleBMC cancer2024

Rate of benign histology after resection of suspected renal cell carcinoma: multicenter comparison between Korea and the United States.

Chang Wook Jeong, Jang Hee Han, Seok Soo Byun, Cheryn Song, Sung-Hoo Hong, Jinsoo Chung, Seong Il Seo, Hong Koo Ha, Eu Chang Hwang, Ill Young Seo and 4 more

Abstract readMulticenter Study
In one paragraph

Article in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chang Wook Jeong *Department of Urology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 03080, Seoul, Korea.
Jang Hee Han *Department of Urology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 03080, Seoul, Korea.
Seok Soo ByunDepartment of Urology, Seoul National University Bundang Hospital, Seongnam, Korea.
Cheryn SongDepartment of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Sung-Hoo HongDepartment of Urology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Jinsoo ChungDepartment of Urology, National Cancer Center, Goyang, Korea.
Seong Il SeoDepartment of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Hong Koo HaDepartment of Urology, Pusan National University Hospital, Busan, Korea.
Eu Chang HwangDepartment of Urology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
Ill Young SeoDepartment of Urology, Institute of Wonkwang Medical Science, Wonkwang University School of Medicine, Iksan, Korea.
Joseph G CheaibDepartment of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Phillip M PierorazioDepartment of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Misop HanDepartment of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Cheol KwakDepartment of Urology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 03080, Seoul, Korea. mdrafael@snu.ac.kr.

Funding

Korea government 1711174374, RS-2020-KD000252
6 · The paper itself

Abstract

backgroundIn the United States, the rate of benign histology among resected renal tumors suspected to be malignant is increasing. We evaluated the rates in the Republic of Korea and assessed the racial effect using recent multi-institutional Korean-United States data.

methodsWe conducted a multi-institutional retrospective study of 11,529 patients (8,812 from The Republic of Korea and 2,717 from the United States) and compared the rates of benign histology between the two countries. To evaluate the racial effect, we divided the patients into Korean, Asian in the US, and Non-Asian in the US.

resultsThe rates of benign histology and small renal masses in Korean patients were significantly lower than that in United States patients (6.3% vs. 14.3%, p < 0.001) and (≤ 4 cm, 7.6% vs. 19.5%, p < 0.001), respectively. Women, incidentaloma, partial nephrectomy, minimally invasive surgery, and recent surgery were associated with a higher rate of benign histology than others.

conclusionsIn Korea, the rate of benign histology among resected renal tumors was significantly lower than that in the United States. This disparity could be caused by environmental or cultural differences rather than racial differences. Our findings suggest that re-evaluating current context-specific standards of care is necessary to avoid overtreatment.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsFemaleHumansKidneyNephrectomyRepublic of KoreaRetrospective StudiesUnited StatesBenign histologyDiagnostic errorsNephrectomyRenal cell carcinoma

Identifiers

PMID38360715
PMCPMC10870474

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.