Evidence map›Paper›PMID 38360704›Full record

ArticleJournal of translational medicine2024

Autophagy inhibition improves the targeted radionuclide therapy efficacy of

Xingyu Liu, Danni Li, Tianbao Ma, Xiu Luo, Ye Peng, Tao Wang, Changjing Zuo, Jianming Cai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The Development of AlPharmaceutics · 2025
    Article
  5. The role of autophagy in pancreatic diseases.Frontiers in pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xingyu LiuSchool of Public Health and Management, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.
Danni LiDepartment of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Tianbao MaDepartment of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Xiu LuoDepartment of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Ye PengDepartment of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
Tao WangDepartment of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China. wangtao2086@smmu.edu.cn.
Changjing ZuoDepartment of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China. cjzuo@smmu.edu.cn.ORCID 0009-0007-9165-8244
Jianming CaiSchool of Public Health and Management, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China. cjm882003@163.com.
Shanghai First People's Hospital · CNNaval Medical Research Command · USWenzhou Medical University · CN

Funding

The National Natural Science Foundation of China 82001867The Special Foundation for Emerging Interdisciplinary Field Research of Shanghai Municipal Health Commission 2022JC004
6 · The paper itself

Abstract

purposesRadiotherapy can induce tumor cell autophagy, which might impair the antitumoral effect. This study aims to investigate the effect of autophagy inhibition on the targeted radionuclide therapy (TRT) efficacy of

methodsHuman pancreatic cancer PANC-1 cells were exposed to

results

conclusions

Indexed as

Fluorodeoxyglucose F18Pancreatic NeoplasmsAnimalsAutophagyCell Line, TumorHumansMiceMice, NudePositron Emission Tomography Computed TomographyRadioisotopesXenograft Model Antitumor AssaysFluorodeoxyglucose F18RadioisotopesAutophagyFAP-2286Pancreatic cancerTargeted radionuclide therapy

Identifiers

PMID38360704
PMCPMC10870561
OpenAlexW4391843915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.