Evidence map›Paper›PMID 38360201›Full record

ArticleBiochimica et biophysica acta. Molecular and cell biology of lipids2024

Role of phosphatidic acid lipids on plasma membrane association of the Ebola virus matrix protein VP40.

Michael D Cioffi, Monica L Husby, Bernard S Gerstman, Robert V Stahelin, Prem P Chapagain

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochimica et biophysica acta. Molecular and cell biology of lipids, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael D CioffiDepartment of Physics, Florida International University, Miami, FL 33199, USA.
Monica L HusbyDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
Bernard S GerstmanDepartment of Physics, Florida International University, Miami, FL 33199, USA; Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, USA.
Robert V StahelinDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA; The Purdue Institute for Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, IN 47907, USA. Electronic address: rstaheli@purdue.edu.
Prem P ChapagainDepartment of Physics, Florida International University, Miami, FL 33199, USA; Biomolecular Sciences Institute, Florida International University, Miami, FL 33199, USA. Electronic address: chapagap@fiu.edu.
Florida International University · USPurdue University West Lafayette · US

Funding

Chemistry-Biochemistry-Biology Training Program at Notre DameT32GM075762 · NIGMS · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F, MOBASHERY, SHAHRIAR · 2007 to 2021
$3.7M
Computational and Biophysical Analysis of the Filovirus Matrix Protein SystemR01AI158220 · NIAID · PURDUE UNIVERSITY · PI STAHELIN, ROBERT VIRGIL, WIEST, OLAF G · 2021 to 2025
$3.6M
Request of a Nikon A1Rsi confocal microscopeS10OD027043 · OD · PURDUE UNIVERSITY · PI STAHELIN, ROBERT VIRGIL · 2019 to 2019
$538k
Investigation of the role of phosphatidic acid metabolism in filovirus buddingR21AI142651 · NIAID · PURDUE UNIVERSITY · PI STAHELIN, ROBERT VIRGIL · 2020 to 2021
$457k
NIAID NIH HHS R01 AI158220NIAID NIH HHS R21 AI142651NIGMS NIH HHS T32 GM075762NIH HHS S10 OD027043
6 · The paper itself

Abstract

The Ebola virus matrix protein VP40 is responsible for the formation of the viral matrix by localizing at the inner leaflet of the human plasma membrane (PM). Various lipid types, including PI(4,5)P

Indexed as

EbolavirusHemorrhagic Fever, EbolaCell MembraneHumansLipidsMolecular Dynamics SimulationLipidsCoarse-grainedEbola virusMatrix protein VP40Molecular Dynamics simulationPhosphatidic acidPhospholipase DPlasma membraneVirus-like particle

Identifiers

PMID38360201
PMCPMC11687635
OpenAlexW4391817772

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.