Evidence map›Paper›PMID 38359966›Full record

ReviewRegional anesthesia and pain medicine2024

Perioperative considerations for patients exposed to hallucinogens.

Trent Emerick, Tetyana Marshall, Thomas Jeff Martin, Doug Ririe

Open access · greenAbstract readReview
In one paragraph

Review in Regional anesthesia and pain medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Trent EmerickDepartment of Anesthesiology and Perioperative Medicine, Chronic Pain Division, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA emericktd@upmc.edu.ORCID 0000-0002-3802-5946
Tetyana MarshallDepartment of Anesthesiology and Perioperative Medicine, UPMC, Pittsburgh, Pennsylvania, USA.
Thomas Jeff MartinPain Mechanisms Lab, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Doug RiriePain Mechanisms Lab, Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Wake Forest University · USUniversity of Pittsburgh Medical Center · USUPMC Health System · US

Funding

Pharmacokinetics/Pharmacodynamics CoreP01NS119159 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI James Eisenach, THOMAS JEFFREY MARTIN · 2022 to 2026
$10.4M
Biased Kappa Opioid Agonists as Non-addictive AnalgesicsR01DA048490 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI JONES, SARA RAULERSON, MARTIN, THOMAS JEFFREY · 2019 to 2023
$3.4M
NIDA NIH HHS R01 DA048490NINDS NIH HHS P01 NS119159
6 · The paper itself

Abstract

Hallucinogen exposure in patients in the perioperative period presents challenges for anesthesiologists and other anesthesia providers. Acute and chronic exposure to these substances can cause physiological impacts that can affect the function of anesthetic and analgesic medications used during perioperative care. The objective of this narrative review is to educate readers on the wide array of hallucinogens and psychedelics that may influence the perioperative management of patients exposed to these substances. A narrative review of the literature surrounding hallucinogens and psychedelics was completed. Hallucinogens and psychedelics are quite varied in their mechanisms of action and therefore present a variety of perioperative implications and perioperative considerations. Many of these substances increase serotonin levels or act directly at serotonergic receptors. However, there are other relevant actions that may include varied mechanisms from N-methyl-D-aspartate receptor antagonism to stimulation of muscarinic receptors. With hallucinogen exposure rates on the rise, understanding the effects of hallucinogens is important for optimizing management and reducing risks perioperatively for patients with acute or chronic exposure.

Indexed as

HallucinogensPerioperative CareHumansHallucinogensDrug-Related Side Effects and Adverse ReactionsNeurotransmitter AgentsPharmacology

Identifiers

PMID38359966
PMCPMC11324860
OpenAlexW4391839665

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.