Evidence map›Paper›PMID 38359349›Full record

ArticleAIDS care2024

The salience of structural barriers and behavioral health problems to ART adherence in people receiving HIV primary care in South Africa.

Steven A Safren, Jasper S Lee, Lena S Andersen, Amelia M Stanton, Ashraf Kagee, Norik Kirakosian, Conall O'Cleirigh, John A Joska

Abstract read
In one paragraph

Article in AIDS care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Steven A SafrenDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Jasper S LeeBehavioral Medicine Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Lena S AndersenGlobal Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Amelia M StantonDepartment of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
Ashraf KageeDepartment of Psychology, Stellenbosch University, Western Cape, South Africa.
Norik KirakosianDepartment of Psychology, University of Miami, Coral Gables, FL, USA.
Conall O'CleirighBehavioral Medicine Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
John A JoskaHIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.

Funding

The University of Miami AIDS Research Center on Mental Health and HIV/AIDS - Center for HIV & Research in Mental Health (CHARM)Research Core & MHD-CEP30MH133399 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Audrey Harkness · 2023 to 2026
$8.9M
Nurse-Delivered CBT for Depression-Adherence in HIV Primary Care S. AfricaR01MH103770 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI O'CLEIRIGH, CONALL MICHAEL, SAFREN, STEVEN A · 2015 to 2019
$3.1M
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
Effects of Syndemics on HIV Outcomes in South AfricaF31MH122279 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI LEE, JASPER SAMUEL · 2020 to 2020
$41k
NIDA NIH HHS K24 DA040489NIMH NIH HHS F31 MH122279NIMH NIH HHS P30 MH133399NIMH NIH HHS R01 MH103770
6 · The paper itself

Abstract

Multilevel factors (individual and structural) influence adherence to antiretroviral therapy, particularly in high HIV prevalence areas such as South Africa. The present study examined the relative importance of structural barriers to HIV care and behavioral health factors, depression and alcohol use, in Khayelitsha, Cape Town, South Africa. People receiving HIV care in six primary care clinics in Khayelitsha (N = 194) completed the Center for Epidemiologic Studies Depression Scale, the Alcohol Use Disorders Identification Test, the Structural Barriers to Medication Taking questionnaire, and a qualitative rating of past-two-week adherence. Correlations were employed to examine associations among these variables, and hierarchical regression analysis was used to examine the unique effects of structural barriers over and above depression and alcohol use as predictors of adherence. Participants were primarily Black South African (99%) women (83%), and 41 years old on average. All four variables were significantly correlated. The hierarchical regression analysis showed that among behavioral health predictors, alcohol use alone significantly predicted ART adherence (b = -.032,

Indexed as

DepressionDrug MonitoringHIV InfectionsMedication AdherencePrimary Health CareAdultAlcohol DrinkingAnti-HIV AgentsFemaleHealth Services AccessibilityHumansMaleMiddle AgedSouth AfricaSurveys and QuestionnairesAnti-HIV Agentsalcohol useART adherencedepressionHIVSDG 10: Reduced inequalitiesSDG 3: Good health and well-beingstructural barriers

Identifiers

PMID38359349
PMCPMC11283988

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.