Evidence map›Paper›PMID 38359118›Full record

ArticleScience (New York, N.Y.)2024

Telomerase misbehaves after a breakup.

Nausica Arnoult, Thomas R Cech

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nausica ArnoultDepartment of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, CO, USA.
Thomas R CechDepartment of Biochemistry and BioFrontiers Institute, University of Colorado Boulder, Boulder, CO, USA.

Funding

Deciphering the role of heterochromatin in telomere function and maintenance mechanismsR35GM143108 · NIGMS · UNIVERSITY OF COLORADO · PI ARNOULT, NAUSICA C. · 2021 to 2025
$1.9M
Deciphering the function of the APE2 nuclease during repair by alternative end-joining and its role in HR-deficient cellsR01CA266100 · NCI · UNIVERSITY OF COLORADO · PI Nausica C. Arnoult · 2022 to 2026
$1.7M
NCI NIH HHS R01 CA266100NIGMS NIH HHS R35 GM143108
6 · The paper itself

Abstract

Suppressing telomerase action at broken DNA preserves genome integrity.

Indexed as

DNA Breaks, Double-StrandedDNA RepairTelomeraseTelomereHumansTelomerase

Identifiers

PMID38359118
PMCPMC11521237

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.