Evidence map›Paper›PMID 38358640›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2024

Chemical Characterization of Phoenix dactylifera L. Seeds and their Beneficial Effects on the Vascular Response in Hypertensive Rats.

Fredi Cifuentes, Javier Palacios, Daniel Asunción-Alvarez, Ricardo D G de Albuquerque, Mario J Simirgiotis, Adrián Paredes, Chukwuemeka R Nwokocha, Raha Orfali, Shagufta Perveen

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Fredi CifuentesDepartamento Biomédico, Facultad Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, 1271155, Chile.ORCID http://orcid.org/0000-0001-5922-8892
Javier PalaciosLaboratorio de Bioquímica Aplicada, Química y Farmacia, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, 1110939, Chile. clpalaci@unap.cl.ORCID http://orcid.org/0000-0002-7997-9295
Daniel Asunción-AlvarezLaboratorio de Bioquímica Aplicada, Química y Farmacia, Facultad de Ciencias de la Salud, Universidad Arturo Prat, Iquique, 1110939, Chile.ORCID http://orcid.org/0000-0001-7498-2121
Ricardo D G de AlbuquerqueLaboratório de Tecnologia em Productos Naturais, Universidade Federal Fluminense, Niterói, Brazil.ORCID http://orcid.org/0000-0002-8442-3849
Mario J SimirgiotisInstituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valaffiliationia, 5090000, Chile.ORCID http://orcid.org/0000-0003-4552-3123
Adrián ParedesLaboratorio de Productos Naturales, Departamento de Química, Facultad de Ciencias Básicas, Universidad de Antofagasta, Antofagasta, 1270300, Chile.ORCID http://orcid.org/0000-0003-3332-8582
Chukwuemeka R NwokochaDepartment of Basic Medical Sciences Physiology Section, Faculty of Medical Sciences, The University of the West Indies, Kingston 7, Mona, Jamaica.ORCID http://orcid.org/0000-0001-7092-9382
Raha OrfaliDepartment of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia.ORCID http://orcid.org/0000-0002-9421-4127
Shagufta PerveenDepartment of Chemistry, School of Computer, Mathematical and Natural Sciences, Morgan State University, Baltimore, MD, 21251, USA. shagufta.perveen@morgan.edu.ORCID http://orcid.org/0000-0002-3318-9861
Arturo Prat University · CLUniversidad de Antofagasta · CLAustral University of Chile · CLKing Saud University · SAMorgan State University · USUniversidade Federal Fluminense · BRUniversity of the West Indies System · JM

Funding

Agencia Nacional de Investigación y Desarrollo 1200610King Saud University RSP2023R431
6 · The paper itself

Abstract

Although Phoenix dactylifera dates are traditionally consumed for their health benefits, no research has been done on the vascular response in hypertensive animals. This study evaluated the vascular relaxation of hydroalcoholic extracts from seeds of three varieties of P. dactylifera; Sukkari seed (SS), Ajwa seed (AS), and Mabroom seed (MS) on L-NAME-induced hypertension and spontaneously hypertensive rats (SHR). Results showed that all extracts (10 µg/mL) caused relaxations higher than 60% in the aortic rings precontracted with 10

Indexed as

HypertensionNG-Nitroarginine Methyl EsterNitric OxidePhoeniceaePlant ExtractsRats, Inbred SHRSeedsAnimalsAntihypertensive AgentsAortaEndothelium, VascularMaleNitric Oxide Synthase Type IIIRatsVasodilationAntihypertensive AgentsNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide Synthase Type IIIPlant ExtractsAortaAwjaMabroomNitric oxideSpontaneously hypertensive ratSukkari

Identifiers

PMID38358640
OpenAlexW4391836974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.