Evidence map›Paper›PMID 38358531›Full record

ArticleAnalytical and bioanalytical chemistry2024

A colorimetric sensing strategy based on chitosan-stabilized platinum nanoparticles for quick detection of α-glucosidase activity and inhibitor screening.

Qin-Qin Yang, Shao-Bin He, Yi-Lin Zhang, Min Li, Xiu-Hua You, Bo-Wen Xiao, Liu Yang, Zhi-Qiang Yang, Hao-Hua Deng, Wei Chen

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Qin-Qin YangExperimental Teaching Center, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China.
Shao-Bin HeFujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China.
Yi-Lin ZhangExperimental Teaching Center, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China.
Min LiExperimental Teaching Center, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China.
Xiu-Hua YouExperimental Teaching Center, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China.
Bo-Wen XiaoExperimental Teaching Center, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China.
Liu YangFujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China.
Zhi-Qiang YangFujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China.
Hao-Hua DengFujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China. DHH8908@163.com.
Wei ChenFujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, School of Pharmacy, Fujian Medical University, Fuzhou, 350004, China. chenandhu@163.com.ORCID http://orcid.org/0000-0003-3233-8877
Fujian Medical University · CN

Funding

Natural Science Foundation of Fujian Province 2022J01271Startup Fund for Scientific Research, Fujian Medical University 2018QH1013Startup Fund for Scientific Research, Fujian Medical University 2019QH1006
6 · The paper itself

Abstract

α-Glucosidase (α-Glu) is implicated in the progression and pathogenesis of type II diabetes (T2D). In this study, we developed a rapid colorimetric technique using platinum nanoparticles stabilized by chitosan (Ch-PtNPs) to detect α-Glu activity and its inhibitor. The Ch-PtNPs facilitate the conversion of 3,3',5,5'-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB) in the presence of dissolved O

Indexed as

alpha-GlucosidasesChitosanColorimetryGlycoside Hydrolase InhibitorsMetal NanoparticlesPlatinumBenzidinesHumansLimit of Detection3,3',5,5'-tetramethylbenzidinealpha-GlucosidasesBenzidinesChitosanGlycoside Hydrolase InhibitorsPlatinumColorimetric detectionInhibitor screeningOxidase-mimicking activityPlatinum nanoparticlesα-Glucosidase

Identifiers

PMID38358531
OpenAlexW4391846328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.