Evidence map›Paper›PMID 38358392›Full record

ArticleeLife2024

Cell-type-specific

Ban Wang, Alexander L Starr, Hunter B Fraser

Open access · goldAbstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Evolution of CTCF binding sites in the human genome.Molecular biology and evolution · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Dichotomous transcriptome divergence at the cell-type level between thebioRxiv : the preprint server for biology · 2025
    Article
  15. The regulatory architecture of gene expression variation inbioRxiv : the preprint server for biology · 2025
    Article
  16. Article
  17. Review
  18. Reconstructing human-specific regulatory functions in model systems.Current opinion in genetics & development · 2024
    Review
  19. Article
  20. Cell-type-specificeLife · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ban Wang *Department of Biology, Stanford University, Stanford, United States.ORCID https://orcid.org/0000-0003-2907-6132
Alexander L Starr *Department of Biology, Stanford University, Stanford, United States.ORCID https://orcid.org/0000-0001-6297-9742
Hunter B FraserDepartment of Biology, Stanford University, Stanford, United States.ORCID https://orcid.org/0000-0001-8400-8541
Stanford University · US

Funding

Investigating human cis-regulatory evolution with hybrid iPS cellsR01HG012285 · NHGRI · STANFORD UNIVERSITY · PI FRASER, HUNTER B · 2022 to 2025
$2.8M
NHGRI NIH HHS R01 HG012285NHGRI NIH HHS R01HG012285
6 · The paper itself

Abstract

Although gene expression divergence has long been postulated to be the primary driver of human evolution, identifying the genes and genetic variants underlying uniquely human traits has proven to be quite challenging. Theory suggests that cell-type-specific

Indexed as

ChromatinPan troglodytesAnimalsGene ExpressionHumansHybrid CellsMotor NeuronsChromatinchimpanzeechromatincis-regulationevolutionary biologygeneticsgenomicshumanhybridnatural selectiontissue-specific

Identifiers

PMID38358392
PMCPMC10942608
OpenAlexW4385840339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.