Evidence map›Paper›PMID 38358051›Full record

ArticleJournal of veterinary internal medicine

Evaluation of risk factors for sleep-disordered breathing in dogs.

Iida Niinikoski, Sari-Leena Himanen, Mirja Tenhunen, Mimma Aromaa, Liisa Lilja-Maula, Minna M Rajamäki

Open access · goldAbstract readObservational Study, Veterinary
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Iida NiinikoskiDepartment of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-9989-8679
Sari-Leena HimanenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mirja TenhunenDepartment of Clinical Neurophysiology, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, Tampere, Finland.ORCID https://orcid.org/0000-0003-0202-8392
Mimma AromaaDepartment of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0001-5162-8146
Liisa Lilja-MaulaDepartment of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.
Minna M RajamäkiDepartment of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland.
University of Helsinki · FIPirkanmaa Hospital District · FITampere University · FI

Funding

Agria Djurförsäkring/Svenska Kennelklubben Forskningsfond N2020-0021Eläinlääketieteen Tutkimuksen TukisäätiöFinnish Canine Health Research FundSuomen Eläinlääketieteen Säätiö
6 · The paper itself

Abstract

backgroundBrachycephalic dogs display sleep-disordered breathing (SDB). The risk factors for SDB remain unknown.

objectivesTo identify risk factors for SDB. We hypothesized that brachycephaly, increasing severity of brachycephalic obstructive airway syndrome (BOAS), excess weight, and aging predispose to SDB. ANIMALS: Sixty-three privately owned pet dogs were prospectively recruited: 28 brachycephalic and 35 normocephalic (mesaticephalic or dolicocephalic) dogs.

methodsProspective observational cross-sectional study with convenience sampling. Recording with the neckband was done over 1 night at each dog's home. The primary outcome measure was the obstructive respiratory event index (OREI). Body condition score (BCS) was assessed, and BOAS severity was graded for brachycephalic dogs.

resultsBrachycephaly was a significant risk factor for high OREI value (ratio of the geometric means 5.6, 95% confidence interval [CI] 3.2-9.9; P < .001) but aging was not (1.1, 95% CI 1.0-1.2; P = .2). Excess weight, defined as a BCS of over 5/9, (3.5, 95% CI 1.8-6.7; P < .001) was a significant risk factor. In brachycephalic dogs, BOAS-positive class (moderate or severe BOAS signs) was a significant risk factor (2.5, 95% CI 1.1-5.6; P = .03). CONCLUSIONS AND CLINICAL IMPORTANCE: Brachycephaly decreases welfare in a multitude of ways, including disrupting sleep. Brachycephaly, increasing severity of BOAS and excess weight are risk factors for obstructive SDB.

Indexed as

Airway ObstructionCraniosynostosesDog DiseasesSleep Apnea SyndromesAnimalsCross-Sectional StudiesDogsRisk Factorsbrachycephalic obstructive airway syndromeobstructive respiratory event indexobstructive sleep apneasleep-disordered breathing

Identifiers

PMID38358051
PMCPMC10937515
OpenAlexW4391847069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.