Evidence map›Paper›PMID 38357843›Full record

ArticleVeterinary medicine and science2024

Antibiotic resistance and virulence profiles of Proteus mirabilis isolated from broiler chickens at abattoir in South Africa.

Tsepo Ramatla, Taole Ramaili, Kgaugelo Lekota, Kealeboga Mileng, Rendani Ndou, Malekoba Mphuthi, Ntelekwane Khasapane, Michelo Syakalima, Oriel Thekisoe

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  5. The Integrative and Conjugative Element ICEThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
  6. Article
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  8. Zoonotic Risks ofMicroorganisms · 2025
    Review
  9. Description on the prevalence ofFrontiers in microbiology · 2025
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Tsepo RamatlaUnit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa.ORCID 0000-0002-0473-8075
Taole RamailiDepartment of Animal Health, School of Agriculture, North-West University, Mmabatho, South Africa.
Kgaugelo LekotaUnit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa.
Kealeboga MilengUnit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa.
Rendani NdouDepartment of Animal Health, School of Agriculture, North-West University, Mmabatho, South Africa.
Malekoba MphuthiDepartment of Animal Health, School of Agriculture, North-West University, Mmabatho, South Africa.
Ntelekwane KhasapaneDepartment of Life Sciences, Centre for Applied Food Safety and Biotechnology, Central University of Technology, Bloemfontein, South Africa.
Michelo SyakalimaDepartment of Animal Health, School of Agriculture, North-West University, Mmabatho, South Africa.
Oriel ThekisoeUnit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa.
North-West University · ZACentral University of Technology · ZAUniversity of the Free State · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProteus mirabilis has been identified as an important zoonotic pathogen, causing several illnesses such as diarrhoea, keratitis and urinary tract infections.

objectiveThis study assessed the prevalence of P. mirabilis in broiler chickens, its antibiotic resistance (AR) patterns, ESBL-producing P. mirabilis and the presence of virulence genes.

methodsA total of 26 isolates were confirmed as P. mirabilis from 480 pooled broiler chicken faecal samples by polymerase chain reaction (PCR). The disk diffusion method was used to evaluate the antibacterial susceptibility test, while nine virulence genes and 26 AR genes were also screened by PCR.

resultsAll 26 P. mirabilis isolates harboured the ireA (siderophore receptors), ptA, and zapA (proteases), ucaA, pmfA, atfA, and mrpA (fimbriae), hlyA and hpmA (haemolysins) virulence genes. The P. mirabilis isolates were resistant to ciprofloxacin (62%) and levofloxacin (54%), while 8 (30.7%) of the isolates were classified as multidrug resistant (MDR). PCR analysis identified the bla

conclusionsThe rise of ciprofloxacin and levofloxacin resistance, as well as MDR strains, is a public health threat that points to a challenge in the treatment of infections caused by these zoonotic bacteria. Furthermore, because ESBL-producing P. mirabilis has the potential to spread to humans, the presence of bla

Indexed as

ChickensProteus mirabilisAbattoirsAnimalsCiprofloxacinDrug Resistance, Multiple, BacterialHumansLevofloxacinSouth AfricaVirulenceCiprofloxacinLevofloxacinantimicrobial resistancebroiler chickensP. mirabilisSouth Africavirulence gene

Identifiers

PMID38357843
PMCPMC10867704
OpenAlexW4391840722

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.