Evidence map›Paper›PMID 38357728›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2024

Lower dynamic cerebral autoregulation following acute bout of low-volume high-intensity interval exercise in chronic stroke compared to healthy adults.

Alicen A Whitaker, Stacey E Aaron, Mark Chertoff, Patrice Brassard, Jake Buchanan, Katherine Nguyen, Eric D Vidoni, Saniya Waghmare, Sarah M Eickmeyer, Robert N Montgomery and 1 more

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. APOE4 carriers display loss of anticipatory cerebrovascular regulation across the Alzheimer's disease continuum.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Alicen A WhitakerDepartment of Physical Therapy, Rehabilitation Science, and Athletic Training, University of Kansas Medical Center, Kansas City, Kansas, United States.ORCID 0000-0002-8701-9227
Stacey E AaronDepartment of Neurology, University of Kansas Medical Center, Kansas City, Kansas, United States.ORCID 0000-0002-2532-8278
Mark ChertoffDepartment of Hearing and Speech, University of Kansas Medical Center, Kansas City, Kansas, United States.
Patrice BrassardDepartment of Kinesiology, Faculty of Medicine, Université Laval, Quebec City, Quebec, Canada.ORCID 0000-0002-6254-5044
Jake BuchananDepartment of Physical Therapy, Rehabilitation Science, and Athletic Training, University of Kansas Medical Center, Kansas City, Kansas, United States.
Katherine NguyenDepartment of Physical Therapy, Rehabilitation Science, and Athletic Training, University of Kansas Medical Center, Kansas City, Kansas, United States.
Eric D VidoniDepartment of Neurology, University of Kansas Medical Center, Kansas City, Kansas, United States.ORCID 0000-0001-5181-7131
Saniya WaghmareDepartment of Physical Therapy, Rehabilitation Science, and Athletic Training, University of Kansas Medical Center, Kansas City, Kansas, United States.
Sarah M EickmeyerDepartment of Physical Medicine and Rehabilitation, University of Kansas Medical Center, Kansas City, Kansas, United States.
Robert N MontgomeryDepartment of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, Kansas, United States.
Sandra A BillingerDepartment of Neurology, University of Kansas Medical Center, Kansas City, Kansas, United States.ORCID 0000-0002-1618-7207
University of Kansas Medical Center · USUniversity of Kansas · USInstitut universitaire de cardiologie et de pneumologie de Québec · CAMedical College of Wisconsin · US

Funding

University of Kansas Alzheimer's Disease Research Center (KU ADRC)P30AG072973 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mohammad Haeri · 2021 to 2026
$25.3M
Heartland Institute for Clinical and Translational ResearchUL1TR000001 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2012 to 2015
$13.0M
Training in Signature Transdisciplinary Cardiovascular SciencesT32HL134643 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Justin L Grobe, Jacquelyn P Kulinski · 2017 to 2026
$4.2M
NRSA Training CoreTL1TR002368 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jennifer Lynn Goldman, NICOLE L NOLLEN · 2017 to 2026
$4.0M
Kansas University Training Program in Neurological and Rehabilitation SciencesT32HD057850 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jacob J. Sosnoff · 2009 to 2026
$3.4M
Minimizing Fall-Related Injury in Older Adults: a motor learning approachR21AG073892 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOSNOFF, JACOB J. · 2021 to 2022
$429k
NCATS NIH HHS TL1 TR002368NCATS NIH HHS UL1 TR000001NHLBI NIH HHS T32 HL134643NIA NIH HHS P30 AG072973NIA NIH HHS R21 AG073892NICHD NIH HHS T32 HD057850
6 · The paper itself

Abstract

Fluctuating arterial blood pressure during high-intensity interval exercise (HIIE) may challenge dynamic cerebral autoregulation (dCA), specifically after stroke after an injury to the cerebrovasculature. We hypothesized that dCA would be attenuated at rest and during a sit-to-stand transition immediately after and 30 min after HIIE in individuals poststroke compared with age- and sex-matched control subjects (CON). HIIE switched every minute between 70% and 10% estimated maximal watts for 10 min. Mean arterial pressure (MAP) and middle cerebral artery blood velocity (MCAv) were recorded. dCA was quantified during spontaneous fluctuations in MAP and MCAv via transfer function analysis. For sit-to-stand, time delay before an increase in cerebrovascular conductance index (CVCi = MCAv/MAP), rate of regulation, and % change in MCAv and MAP were measured. Twenty-two individuals poststroke (age 60 ± 12 yr, 31 ± 16 mo) and twenty-four CON (age 60 ± 13 yr) completed the study. Very low frequency (VLF) gain (

Indexed as

ExerciseStrokeAdultAgedArterial PressureBlood Flow VelocityBlood PressureCerebrovascular CirculationHomeostasisHumansMiddle AgedMiddle Cerebral Arterycerebral autoregulationcerebral blood flowcerebral hemodynamicsphysical therapyrehabilitation

Identifiers

PMID38357728
PMCPMC11286270
OpenAlexW4391872791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.