Evidence map›Paper›PMID 38357661›Full record

ArticleiScience2024

Third-generation taxanes SB-T-121605 and SB-T-121606 are effective in pancreatic ductal adenocarcinoma.

Tomas Sychra, Alzbeta Spalenkova, Stepan Balatka, Radka Vaclavikova, Karolina Seborova, Marie Ehrlichova, Jaroslav Truksa, Cristian Sandoval-Acuña, Vlasta Nemcova, Arpad Szabo and 6 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Tomas SychraDepartment of Surgery, University Hospital Kralovske Vinohrady, 100 00 Prague, Czech Republic.
Alzbeta SpalenkovaToxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Stepan BalatkaToxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Radka VaclavikovaToxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Karolina SeborovaToxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Marie EhrlichovaToxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Jaroslav TruksaInstitute of Biotechnology of the Czech Academy of Sciences, BIOCEV Research Center, 252 50 Vestec, Czech Republic.
Cristian Sandoval-AcuñaInstitute of Biotechnology of the Czech Academy of Sciences, BIOCEV Research Center, 252 50 Vestec, Czech Republic.
Vlasta NemcovaDepartment of Biochemistry, Cell and Molecular Biology, Third Faculty of Medicine, Charles University, 100 00 Prague, Czech Republic.
Arpad SzaboThird Faculty of Medicine, Charles University, 100 00 Prague, Czech Republic.
Kamila KociThird Faculty of Medicine, Charles University, 100 00 Prague, Czech Republic.
Tereza TesarovaToxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Lei ChenInstitute of Chemical Biology & Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY 11794-3400, USA.
Iwao OjimaInstitute of Chemical Biology & Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY 11794-3400, USA.
Martin OliveriusDepartment of Surgery, University Hospital Kralovske Vinohrady, 100 00 Prague, Czech Republic.
Pavel SoucekToxicogenomics Unit, National Institute of Public Health, 100 00 Prague, Czech Republic.
Charles University · CZCzech Academy of Sciences, Institute of Biotechnology · CZState University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is a severe malignancy with increasing incidence and high mortality due to late diagnosis and low sensitivity to treatments. Search for the most appropriate drugs and therapeutic regimens is the most promising way to improve the treatment outcomes of the patients. This study aimed to compare (1)

Indexed as

CancerCell biologyPharmacology

Identifiers

PMID38357661
PMCPMC10865389
OpenAlexW4391247389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.