Evidence map›Paper›PMID 38357651›Full record

ReviewFrontiers in medicine2024

Type 3 gastric neuroendocrine neoplasms: the rising promise of conservative endoscopic management.

Elisabetta Dell'Unto, Gianluca Esposito, Maria Rinzivillo, Matteo Marasco, Bruno Annibale, Francesco Panzuto

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elisabetta Dell'UntoDepartment of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Gianluca EspositoDepartment of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Maria RinzivilloDigestive Disease Unit, Sant'Andrea University Hospital, ENETS Center of Excellence, Rome, Italy.
Matteo MarascoDepartment of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Bruno AnnibaleDepartment of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Francesco PanzutoDepartment of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITAzienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric neuroendocrine neoplasms (g-NENs) are rare tumors arising from the gastric enterochromaffin-like cells. Recent data suggests an increased detection rate, attributed to more frequent esophagogastroduodenoscopies. While type 3 g-NENs were historically deemed aggressive, emerging research indicates potential for conservative management, especially endoscopic resection, in well-differentiated, small tumors. European guidelines now advocate for endoscopic intervention in selected cases, but North American guidelines remain more conservative. Key factors influencing outcomes are tumor size, grading, and depth of gastric wall infiltration. Endoscopic resection has shown promise for tumors confined to submucosal layers without lymphovascular invasion. Given the complexities, a multidisciplinary team approach is essential for management decisions. Current insights are largely based on retrospective studies, underscoring the need for prospective research to optimize endoscopic approaches.

Indexed as

endoscopic resectiongastric carcinoidsguidelinesmanagementneuroendocrine tumors

Identifiers

PMID38357651
PMCPMC10864619
OpenAlexW4391399997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.