Evidence map›Paper›PMID 38356901›Full record

ArticleClinical psychology in Europe2023

Building an Early Warning System for Depression: Rationale, Objectives, and Methods of the WARN-D Study.

Eiko I Fried, Ricarda K K Proppert, Carlotta L Rieble

Registry-linked trialAbstract read
In one paragraph

Article in Clinical psychology in Europe, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07471529 (Activating Social Resources in Psychotherapy-Seeking Individuals), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07471529 narecruitingnot on this mapstarted 2026, after this paper: background citation

Activating Social Resources in Psychotherapy-Seeking Individuals: Effectiveness and Timing of a Social Support Just-in-Time Adaptive Intervention

TypeinterventionalSponsorUniversity of ZurichRan2026 to 2026Enrolled120ConditionsLoneliness, Social Support, Depressive SymptomsArmsSocial Support Just-in-Time Adaptive Intervention
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eiko I FriedDepartment of Clinical Psychology, Leiden University, Leiden, The Netherlands.ORCID https://orcid.org/0000-0001-7469-594X
Ricarda K K ProppertDepartment of Clinical Psychology, Leiden University, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-4225-2439
Carlotta L RiebleDepartment of Clinical Psychology, Leiden University, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-4764-3906

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Depression is common, debilitating, often chronic, and affects young people disproportionately. Given that only 50% of patients improve under initial treatment, experts agree that prevention is the most effective way to change depression's global disease burden. The biggest barrier to successful prevention is to identify individuals at risk for depression in the near future. To close this gap, this protocol paper introduces the WARN-D study, our effort to build a personalized early warning system for depression. Method: To develop the system, we follow around 2,000 students over 2 years. Stage 1 comprises an extensive baseline assessment in which we collect a broad set of predictors for depression. Stage 2 lasts 3 months and zooms into participants' daily experiences that may predict depression; we use smartwatches to collect digital phenotype data such as sleep and activity, and we use a smartphone app to query participants about their experiences 4 times a day and once every Sunday. In Stage 3, we follow participants for 21 months, assessing transdiagnostic outcomes (including stress, functional impairment, anxiety, and depression) as well as additional predictors for future depression every 3 months. Collected data will be utilized to build a personalized prediction model for depression onset. Discussion: Overall, WARN-D will function similarly to a weather forecast, with the core difference that one can only seek shelter from a thunderstorm and clean up afterwards, while depression may be successfully prevented before it occurs.

Indexed as

depressiondigital healthearly warning systemecological momentary assessmentpredictionpreventionstudent mental health

Identifiers

PMID38356901
PMCPMC10863640

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.