Evidence map›Paper›PMID 38356827›Full record

ArticlePakistan journal of medical sciences

Effect of calcium plus Vitamin-D combined with calcitriol in the treatment of patients with Type-2 diabetes and osteoporosis: A retrospective observational analysis.

Jinxing Wan, Jun Xie, Chaohui Hu, Jiahe Liu, Chunyan Zhu

Open access · goldAbstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jinxing WanJin Xing Wan, Department of Endocrinology, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou Peoples Hospital Zhejiang Province 100 Minjiang Avenue, Quzhou City, Zhejiang Province 324000, P.R. China.
Jun XieJun Xie Department of Orthopedics, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou Peoples Hospital Zhejiang Province 100 Minjiang Avenue, Quzhou City, Zhejiang Province 324000, P.R. China.
Chaohui HuChaohui Hu Department of Endocrinology, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou Peoples Hospital Zhejiang Province 100 Minjiang Avenue, Quzhou City, Zhejiang Province 324000, P.R. China.
Jiahe LiuJiahe Liu Department of Endocrinology, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou Peoples Hospital Zhejiang Province 100 Minjiang Avenue, Quzhou City, Zhejiang Province 324000, P.R. China.
Chunyan ZhuChunyan Zhu Department of Endocrinology, Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou Peoples Hospital Zhejiang Province 100 Minjiang Avenue, Quzhou City, Zhejiang Province 324000, P.R. China.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the clinical effect of calcium plus Vitamin-D combined with calcitriol in the treatment of patients with type-2 diabetes mellitus (T2DM) patients and osteoporosis. Methods: In this retrospective observational study clinical records of 90 patients with T2DM combined with osteoporosis, treated in The Quzhou Affiliated Hospital of Wenzhou Medical University from October 2019 to April 2022 were incuded. All patients received basic hypoglycemic treatment. Of 90 patients, 43 received calcium plus Vitamin-D adjuvant therapy (Control-group), and 47 patients received calcium plus Vitamin-D combined with calcitriol adjuvant therapy (Observation-group). Clinical efficacy, adverse reactions, bone metabolism levels, and changes in bone density levels were compared between the two groups. Results: The clinical efficacy of the treatment was significantly higher in the Observation-group (93.6%) compared to the Control-group (83.7%; Conclusions: Combination of calcium plus Vitamin-D and calcitriol adjuvant therapy in patients with T2DM and osteoporosis is safe and associated with better treatment efficacy, improved bone metabolism and bone density parameters than calcium plus Vitamin-D treatment alone.

Indexed as

CalcitriolCalcium plus Vitamin-DOsteoporosisType-2 diabetes

Identifiers

PMID38356827
PMCPMC10862466
OpenAlexW4389830997

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.