ArticleSports medicine - open2024
The Effects of a Carbohydrate Hydrogel System for the Delivery of Bicarbonate Mini-Tablets on Acid-Base Buffering and Gastrointestinal Symptoms in Resting Well-trained Male Cyclists.
Article in Sports medicine - open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Gastrointestinal Symptoms Associated With Sodium Bicarbonate Supplementation Protocols: A Systematic Review.European journal of sport science · 2026Pooled it
- Negligible benefit of oral single-dose sodium bicarbonate on continuous running performance: systematic review with meta-analysis of randomized, double-blind, placebo-controlled trials.Journal of the International Society of Sports Nutrition · 2025Pooled it
- Bicarbonate and Carbohydrate Co-Ingestion During Exercise in a Novel Gel Format Improves Time-Trial Performance After 3 h of Moderate-Intensity Exercise in Trained Cyclists.Scandinavian journal of medicine & science in sports · 2026Trial
- The effect of sodium bicarbonate mini-tablets in a carbohydrate hydrogel on prolonged high-intensity cycling performance and metabolism in acute normobaric hypoxia.European journal of applied physiology · 2026Trial
- Trial
- The effect of sodium bicarbonate mini-tablets ingested in a carbohydrate hydrogel system on 40 km cycling time trial performance and metabolism in trained male cyclists.European journal of applied physiology · 2024Trial
- Delaying task failure in high-intensity exercise: a Pi-afferent-effort framework for targeted sports nutrition.Journal of the International Society of Sports Nutrition · 2026Review
- Common questions and misconceptions of sodium bicarbonate as an ergogenic aid: what does the science really show?Journal of the International Society of Sports Nutrition · 2026Review
- Design-Driven Gel-Based Delivery Systems for Bioactives in Sports Nutrition.Gels (Basel, Switzerland) · 2026Review
- Prevalence, implementation, and barriers of sodium bicarbonate supplementation in team sports.Biology of sport · 2026Article
- From Science to Dressing Room: Dietary Supplements for Elite Soccer Performance.Journal of functional morphology and kinesiology · 2025Review
- Nutritional Strategies to Improve Post-exercise Recovery and Subsequent Exercise Performance: A Narrative Review.Sports medicine (Auckland, N.Z.) · 2025Review
- Enhancing exercise performance and recovery through sodium bicarbonate supplementation: introducing the ingestion recovery framework.European journal of applied physiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA new commercially available sodium bicarbonate (SB) supplement claims to limit gastrointestinal (GI) discomfort and increase extracellular buffering capacity. To date, no available data exists to substantiate such claims. Therefore, the aim of this study was to measure blood acid-base balance and GI discomfort responses following the ingestion of SB using the novel "Bicarb System" (M-SB). Twelve well-trained male cyclists completed this randomised crossover designed study. Maximal oxygen consumption was determined in visit one, whilst during visits two and three participants ingested 0.3 g∙kg
resultsPeak HCO
conclusionsThis is the first study to report that M-SB can increase buffering capacity and reduce GI discomfort. This presents a major potential benefit for athletes considering SB as an ergogenic supplement as GI discomfort is almost eliminated. Future research should determine if M-SB is performance enhancing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.