Evidence map›Paper›PMID 38355651›Full record

ArticleItalian journal of pediatrics2024

Record of strep throat infections in Italy: what is needed to know about penicillin allergy? The point of view from the Italian Society of Pediatric Allergy and Immunology (SIAIP).

Maria De Filippo, Angela Klain, Ilaria Brambilla, Silvia Caimmi, Riccardo Castagnoli, Cristiana Indolfi, Giulio Dinardo, Amelia Licari, Alberto Martelli, Maria Angela Tosca and 3 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Italian journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Maria De FilippoDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, Pediatric Unit, University of Pavia, Pavia, Italy.
Angela KlainDepartment of Woman, Child, and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy.
Ilaria BrambillaDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, Pediatric Unit, University of Pavia, Pavia, Italy.
Silvia CaimmiDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, Pediatric Unit, University of Pavia, Pavia, Italy.
Riccardo CastagnoliDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, Pediatric Unit, University of Pavia, Pavia, Italy.
Cristiana IndolfiDepartment of Woman, Child, and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy. cristianaind@hotmail.com.ORCID http://orcid.org/0000-0002-9513-193X
Giulio DinardoDepartment of Woman, Child, and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy.
Amelia LicariDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, Pediatric Unit, University of Pavia, Pavia, Italy.
Alberto MartelliPediatric Unit, PO Garbagnate Milanese, ASST Rhodense, Milan, Italy.
Maria Angela ToscaAllergy Clinic, IRCCS Giannina Gaslini, Genoa, Italy.
Martina VottoDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, Pediatric Unit, University of Pavia, Pavia, Italy.
Gian Luigi Marseglia *Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, Pediatric Unit, University of Pavia, Pavia, Italy.
Michele Miraglia Del Giudice *Department of Woman, Child, and General and Specialized Surgery, University of Campania Luigi Vanvitelli, Naples, Italy.
University of Pavia · ITUniversity of Campania "Luigi Vanvitelli" · ITATS Sardegna (Italy) · ITIstituto Giannina Gaslini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Notifications of invasive group A streptococcal (iGAS) infections have significantly increased in many European Countries compared to the previous season. In Italy, there has been an increase in streptococcal pharyngitis and scarlet fever cases since January 2023, which sparked concerns about a GAS epidemic in the pediatric population. This rise may be ascribed to the GAS infection season that began earlier than usual (off-season outbreak) and the increase in the spread of respiratory viruses and viral coinfections that raised the risk of iGAS disease. Moreover, this phenomenon was also facilitated by increased travel after reduced GAS circulation during the COVID-19 pandemic.The increase in cases of GAS disease has raised some critical issues regarding the potential reactions to administering amoxicillin, the first-line antibiotic therapy, many of which have been erroneously labeled as "allergy."For these reasons, the Italian Society of Pediatric Allergy and Immunology (SIAIP) intends to provide simple clinical indications to help pediatricians manage GAS pharyngitis, discerning the allergic from non-allergic drug hypersensitivity.

Indexed as

Drug HypersensitivityHypersensitivityPharyngitisScarlet FeverStreptococcal InfectionsAnti-Bacterial AgentsChildHumansPandemicsPenicillinsPharynxAnti-Bacterial AgentsPenicillinsAmoxicillinDrug hypersensitivityGroup A streptococcusImmediate reactions (IRs)Invasive group A streptococcal (iGAS) infectionNon-immediate reactions (NIRs)Pharyngitis

Identifiers

PMID38355651
PMCPMC10865528
OpenAlexW4391818152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.