Evidence map›Paper›PMID 38355644›Full record

ArticleNature communications2024

A deep-learning-based framework for identifying and localizing multiple abnormalities and assessing cardiomegaly in chest X-ray.

Weijie Fan, Yi Yang, Jing Qi, Qichuan Zhang, Cuiwei Liao, Li Wen, Shuang Wang, Guangxian Wang, Yu Xia, Qihua Wu and 28 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Weijie Fan *Department of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.ORCID 0009-0005-2961-2689
Yi Yang *Department of Digital Medicine, School of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing, 400038, P. R. China.ORCID 0009-0003-9070-8976
Jing Qi *Department of Digital Medicine, School of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing, 400038, P. R. China.
Qichuan ZhangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Cuiwei LiaoDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Li WenDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Shuang WangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Guangxian WangDepartment of Radiology, People's Hospital of Banan, Chongqing Medical University, Chongqing, 401320, P. R. China.
Yu XiaDepartment of Radiology, Xishui hospital of Traditional Chinese Medicine, Zunyi of Guizhou province, 564600, P. R. China.
Qihua WuDepartment of Radiology, People's Hospital of Nanchuan, Chongqing, 408400, P. R. China.
Xiaotao FanDepartment of Radiology, Fengdu People's Hospital, Chongqing, 408200, P. R. China.
Xingcai ChenDepartment of Digital Medicine, School of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing, 400038, P. R. China.
Mi HeDepartment of Digital Medicine, School of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing, 400038, P. R. China.
JingJing XiaoDepartment of Medical Engineering, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Liu YangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Yun LiuDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Jia ChenDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Bing WangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Lei ZhangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Liuqing YangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Hui GanDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Shushu ZhangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Guofang LiuDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Xiaodong GeDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Yuanqing CaiDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Gang ZhaoDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Xi ZhangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Mingxun XieDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Huilin XuDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Yi ZhangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Jiao ChenDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Jun LiDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Shuang HanDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Ke MuDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Shilin XiaoDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Tingwei XiongDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China.
Yongjian NianDepartment of Digital Medicine, School of Biomedical Engineering and Imaging Medicine, Army Medical University, Chongqing, 400038, P. R. China. yjnian@tmmu.edu.cn.ORCID 0000-0001-6779-0850
Dong ZhangDepartment of Radiology, Second Affiliated Hospital, Army Medical University, Chongqing, 400037, P. R. China. hszhangd@tmmu.edu.cn.ORCID 0000-0003-0332-1195

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate identification and localization of multiple abnormalities are crucial steps in the interpretation of chest X-rays (CXRs); however, the lack of a large CXR dataset with bounding boxes severely constrains accurate localization research based on deep learning. We created a large CXR dataset named CXR-AL14, containing 165,988 CXRs and 253,844 bounding boxes. On the basis of this dataset, a deep-learning-based framework was developed to identify and localize 14 common abnormalities and calculate the cardiothoracic ratio (CTR) simultaneously. The mean average precision values obtained by the model for 14 abnormalities reached 0.572-0.631 with an intersection-over-union threshold of 0.5, and the intraclass correlation coefficient of the CTR algorithm exceeded 0.95 on the held-out, multicentre and prospective test datasets. This framework shows an excellent performance, good generalization ability and strong clinical applicability, which is superior to senior radiologists and suitable for routine clinical settings.

Indexed as

Abnormalities, MultipleDeep LearningCardiomegalyHumansProspective StudiesX-Rays

Identifiers

PMID38355644
PMCPMC10867134

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.