SynthesisBMC medicine2024
Efficacy of virtual reality for pain relief in medical procedures: a systematic review and meta-analysis.
Synthesis in BMC medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 50 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
VIrtual Reality Induced Pain and anxiEty Relief in Outpatient UROlogical Procedures: a Post-marketing Clinical Investigation of REALICA
The Effect of Virtual Reality Headset Use on Pain, Comfort, and Psychosocial Symptoms in Children Undergoing Hypospadias Surgery: A Randomized Controlled Trial.
Who cites it
50 citing papers in PubMed, 7 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Effectiveness and Safety of Virtual Reality Interventions for Symptom Management in Adults Undergoing Hemodialysis: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Effectiveness of Virtual Reality for Pain Relief in Procedures Related to Obstetrics and Gynaecology: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.BJOG : an international journal of obstetrics and gynaecology · 2026Pooled it
- Efficacy of Virtual Reality in Managing Pain for Patients in Palliative Care: A Systematic Review and Meta-Analysis.Journal of pain and symptom management · 2026Pooled it
- The effects of virtual reality on pain relief in ICU patients: meta-analysis and systematic review.Frontiers in medicine · 2026Pooled it
- The impact of virtual reality (VR) on pain management in the emergency department: a systematic review and meta-analysis.BMC emergency medicine · 2025Pooled it
- Comparative efficacy of various physical therapies on pain, fatigue, quality of life and functional impairment in breast cancer survivors: a network meta-analysis of randomized controlled trials.Frontiers in oncology · 2025Pooled it
- Patients' experiences with the application of medical adhesives to the skin: a qualitative systematic review.BMJ open · 2024Pooled it
- Feasibility and Acceptability of Perioperative Application of Biofeedback-Based Virtual Reality vs Control for Pain and Anxiety in Children and Adolescents Undergoing Surgery: Pilot Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Effects of Virtual Reality on Postoperative Pain Management Following Minimally Invasive Gynecologic Surgery: Randomized Controlled Trial.JMIR formative research · 2026Trial
- Effects of pre-procedural video education and intra-procedural virtual reality on anxiety and pain during flexible cystoscopy: a randomized controlled trial.BMC urology · 2026Trial
- Effect of immersive virtual reality on fear, anxiety, and pain in pregnant women during vaginal examination in clinical training: a randomized controlled trial.Scientific reports · 2026Trial
- Effect of virtual reality on pain and anxiety during colonoscopy: A randomized control trial.The Journal of international medical research · 2026Trial
- Feasibility of Mobile Phone-Based Virtual Reality as a Non-pharmacologic Acute Procedural Pain Management Intervention in an Inpatient Burn Center.Journal of clinical psychology in medical settings · 2026Trial
- Randomized controlled study on the use of virtual reality for pain relief in oocyte retrieval under transvaginal ultrasound guidance using paracervical block and conscious sedation.Human reproduction (Oxford, England) · 2025Trial
- Virtual Reality for Anxiety and Pain Management in Lower Limb Orthopedic Surgery Under Spinal Anesthesia: A Randomized Controlled Trial.Health science reports · 2026Article
- A scoping review of virtual reality technology utilization in patients with colorectal cancer.BMC nursing · 2026Article
- Voluntary attention regulates acute immune responses in humans.Nature human behaviour · 2026Article
- Immediate and Short-Term Effects of Nature-Based Immersive Virtual Reality During Dry Needling: A Single-Blinded Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Barriers and facilitators to the implementation of virtual reality as a pain management intervention in outpatient physiotherapy practices: a qualitative analysis.BMC health services research · 2026Article
- The Effect of Virtual Reality Glasses Application During Urodynamics on Procedural Pain, Anxiety, and Hemodynamic Parameters: A Randomized Controlled Trial.International neurourology journal · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundEffective pain control is crucial to optimise the success of medical procedures. Immersive virtual reality (VR) technology could offer an effective non-invasive, non-pharmacological option to distract patients and reduce their experience of pain. We aimed to evaluate the efficacy of Immersive virtual reality (VR) technology in reducing patient's pain perception during various medical procedures by conducting a systematic review and meta-analysis.
methodsWe searched MEDLINE, EMBASE, CENTRAL, CINAHL, and SIGLE until December 2022 for all randomised clinical trials (RCT) evaluating any type of VR in patients undergoing any medical procedure. We conducted a random effect meta-analysis summarising standardised mean differences (SMD) with 95% confidence intervals (CI). We evaluated heterogeneity using I
resultsIn total, we included 92 RCTs (n = 7133 participants). There was a significant reduction in pain scores with VR across all medical procedures (n = 83, SMD - 0.78, 95% CI - 1.00 to - 0.57, I
conclusionsImmersive VR technology offers effective pain control across various medical procedures, albeit statistical heterogeneity. Further research is needed to inform the safe adoption of this technology across different medical disciplines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.