Evidence map›Paper›PMID 38354066›Full record

Trial reportAmerican journal of respiratory and critical care medicine2024

Zinpentraxin Alfa for Idiopathic Pulmonary Fibrosis: The Randomized Phase III STARSCAPE Trial.

Luca Richeldi, Courtney Schiffman, Jürgen Behr, Yoshikazu Inoue, Tamera J Corte, Vincent Cottin, R Gisli Jenkins, Steven D Nathan, Ganesh Raghu, Simon L F Walsh and 3 more

Abstract readRandomized Controlled TrialClinical Trial, Phase IIIMulticenter Study
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Acute exacerbation in fibrotic interstitial lung disease: an international working group report.American journal of respiratory and critical care medicine · 2026
    Review
  6. Multi-omics insights into the mechanisms and prognosis of IPF.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2026
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Immunological mechanisms and therapeutic approaches in pulmonary fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  13. Review
  14. Article
  15. Review
  16. The intersection of liver cirrhosis and pulmonary fibrosis.Journal of translational medicine · 2025
    Review
  17. Review
  18. Scar wars: the viral menace.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Luca RicheldiFondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0001-8594-1448
Courtney SchiffmanGenentech, Inc., South San Francisco, California.
Jürgen BehrDepartment of Medicine V, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center, Member of the German Center for Lung Research, Munich, Germany.ORCID 0000-0002-9151-4829
Yoshikazu InoueClinical Research Center, NHO Kinki Chuo Chest Medical Center, Osaka, Japan.ORCID 0000-0003-3994-874X
Tamera J CorteRoyal Prince Alfred Hospital and University of Sydney, Sydney, Australia.ORCID 0000-0002-5076-8929
Vincent CottinNational Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon, National Research Institute for Agriculture, Food and the Environment, European Reference Network for Rare Respiratory Diseases, Lyon, France.ORCID 0000-0002-5591-0955
R Gisli JenkinsImperial NIHR Biomedical Research Centre, National Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0002-7929-2119
Steven D NathanInova Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, Virginia.ORCID 0000-0002-6270-1617
Ganesh RaghuUniversity of Washington Medical Center, Seattle, Washington.
Simon L F WalshImperial NIHR Biomedical Research Centre, National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Parminderjit K JayiaRoche Products Ltd., Welwyn Garden City, United Kingdom; and.
Nikhil KamathRoche Products Ltd., Welwyn Garden City, United Kingdom; and.
Fernando J MartinezWeill Cornell Medical College, New York-Presbyterian Hospital, New York, New York.ORCID 0000-0002-2412-3182

Funding

F. Hoffmann-La Roche, Ltd.
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Idiopathic Pulmonary FibrosisAgedDouble-Blind MethodFemaleHumansMaleMiddle AgedTreatment OutcomeVital Capacityantifibrotic medicationforced vital capacityfutility analysisinterstitial lung diseaselinear mixed-effects model

Identifiers

PMID38354066
PMCPMC11092957

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.