Evidence map›Paper›PMID 38353877›Full record

ArticleAIDS and behavior2024

Acceptability of a Randomized Trial of Anti-depressant Medication or Interpersonal Therapy for Treatment of Perinatal Depression in Women with HIV.

M Bridget Spelke, Eunice Okumu, Nzi R Perry, Bryan S Blette, Ravi Paul, Crystal E Schiller, J M Ncheka, Margaret P Kasaro, Joan T Price, Samantha Meltzer-Brody and 2 more

Open access · hybridAbstract read
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In one paragraph

Article in AIDS and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

M Bridget SpelkeDepartment of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA. bspelke@email.unc.edu.ORCID http://orcid.org/0000-0002-5950-8197
Eunice OkumuSocial and Behavioral Science Core, Center for AIDS Research, University of North Carolina, Chapel Hill, USA.
Nzi R PerrySocial and Behavioral Science Core, Center for AIDS Research, University of North Carolina, Chapel Hill, USA.
Bryan S BletteDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, USA.
Ravi PaulDepartment of Psychiatry, University of Zambia School of Medicine, Lusaka, Zambia.
Crystal E SchillerDepartment of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, USA.
J M NchekaDepartment of Psychiatry, University of Zambia School of Medicine, Lusaka, Zambia.
Margaret P KasaroUniversity of North Carolina - Global Projects Zambia, 348 Independence Ave, Lusaka, Zambia, 10101.
Joan T PriceDepartment of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA.
Samantha Meltzer-BrodyDepartment of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, USA.
Jeffrey S A StringerDepartment of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA.
Elizabeth M StringerDepartment of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA.
University of North Carolina at Chapel Hill · USUniversity of Zambia · ZMVanderbilt University Medical Center · US

Funding

A Career Development Award in Global Postpartum HealthK01TW012426 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mae Bridget Spelke · 2022 to 2026
$922k
A pilot trial of perinatal depression treatment in HIV infected womenR21MH115806 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STRINGER, ELIZABETH MCPHILLIPS · 2018 to 2019
$347k
FIC NIH HHS K01 TW012426FIC NIH HHS K01TW012426NIMH NIH HHS 1R21MH115806NIMH NIH HHS R21 MH115806
6 · The paper itself

Abstract

Postpartum depression (PPD) affects nearly 20% of postpartum women in Sub-Saharan Africa (SSA), where HIV prevalence is high. Depression is associated with worse HIV outcomes in non-pregnant adults and mental health disorders may worsen HIV outcomes for postpartum women and their infants. PPD is effectively treated with psychosocial or pharmacologic interventions; however, few studies have evaluated the acceptability of treatment modalities in SSA. We analyzed interviews with 23 postpartum women with HIV to assess the acceptability of two depression treatments provided in the context of a randomized trial. Most participants expressed acceptability of treatment randomization and study visit procedures. Participants shared perceptions of high treatment efficacy of their assigned intervention. They reported ongoing HIV and mental health stigma in their communities and emphasized the importance of social support from clinic staff. Our findings suggest a full-scale trial of PPD treatment will be acceptable among women with HIV in Zambia.

Indexed as

Depression, PostpartumDepressive DisorderHIV InfectionsAdultDepressionFemaleHumansPostpartum PeriodPregnancyRandomized Controlled Trials as TopicTreatment OutcomeAntidepressant medicationDepressionHIVInterpersonal therapyLow resource settingZambia

Identifiers

PMID38353877
PMCPMC10940463
OpenAlexW4391813413

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.