Evidence map›Paper›PMID 38353533›Full record

ArticlemSphere2024

Dynamics and quantitative contribution of the aminoglycoside 6'-

Ophélie d'Udekem d'Acoz, Fong Hue, Tianyi Ye, Louise Wang, Maxime Leroux, Lucila Rajngewerc, Tung Tran, Kimberly Phan, Maria S Ramirez, Walter Reisner and 2 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Ophélie d'Udekem d'AcozDepartment of Biology, McGill University, Montréal, Québec, Canada.ORCID 0009-0008-7368-725X
Fong HueCenter for Applied Biotechnology Studies, California State University Fullerton, Fullerton, California, USA.
Tianyi YeDepartment of Biology, McGill University, Montréal, Québec, Canada.
Louise WangDepartment of Biology, McGill University, Montréal, Québec, Canada.
Maxime LerouxDepartment of Biology, McGill University, Montréal, Québec, Canada.
Lucila RajngewercCenter for Applied Biotechnology Studies, California State University Fullerton, Fullerton, California, USA.
Tung TranCenter for Applied Biotechnology Studies, California State University Fullerton, Fullerton, California, USA.
Kimberly PhanCenter for Applied Biotechnology Studies, California State University Fullerton, Fullerton, California, USA.
Maria S RamirezCenter for Applied Biotechnology Studies, California State University Fullerton, Fullerton, California, USA.ORCID 0000-0002-9904-7890
Walter ReisnerDepartment of Physics, McGill University, Montréal, Québec, Canada.
Marcelo E TolmaskyCenter for Applied Biotechnology Studies, California State University Fullerton, Fullerton, California, USA.ORCID 0000-0002-6298-7811
Rodrigo Reyes-LamotheDepartment of Biology, McGill University, Montréal, Québec, Canada.ORCID 0000-0002-5330-3481
California State University, Fullerton · USMcGill University · CA

Funding

Minority Health and Health Disparities International Research Training ProgramT37MD001368 · NIMHD · CALIFORNIA STATE UNIVERSITY FULLERTON · PI TOLMASKY, MARCELO E · 2005 to 2024
$3.9M
DEALING WITH ANTIBIOTIC RESISTANCE--ANTISENSE TECHNOLOGYR15AI047115 · NIAID · CALIFORNIA STATE UNIVERSITY FULLERTON · PI TOLMASKY, MARCELO E · 2000 to 2022
$1.8M
Identifying host human products responsible for natural transformation of resistance traits in Acinetobacter sppSC3GM125556 · NIGMS · CALIFORNIA STATE UNIVERSITY FULLERTON · PI RAMIREZ, MARIA SOLEDAD · 2018 to 2025
$851k
NIAID NIH HHS R15 AI047115NIGMS NIH HHS SC3 GM125556NIMHD NIH HHS T37 MD001368
6 · The paper itself

Abstract

Aminoglycosides are essential components in the available armamentarium to treat bacterial infections. The surge and rapid dissemination of resistance genes strongly reduce their efficiency, compromising public health. Among the multitude of modifying enzymes that confer resistance to aminoglycosides, the aminoglycoside 6'-

Indexed as

AmikacinAnti-Bacterial AgentsAcetyltransferasesAminoglycosidesEscherichia coliHumansAcetyltransferasesAmikacinaminoglycoside N(6')-acetyltransferaseAminoglycosidesAnti-Bacterial AgentsAAC(6′)-Ibamikacinantibiotic resistanceCRISPRiEscherichia colifluorescenceplasmid

Identifiers

PMID38353533
PMCPMC10964403
OpenAlexW4391822583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.