Observational studyImmunity, inflammation and disease2024
Association between preoperative systemic immune inflammation index and postoperative sepsis in patients with intestinal obstruction: A retrospective observational cohort study.
Observational study in Immunity, inflammation and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 11 citations in OpenAlex.
- Preoperative inflammatory indicators predict postoperative SIRS after cardiac surgery with cardiopulmonary bypass in older patients.BMC geriatrics · 2026Article
- Predicting Wound Complications Following Total Knee Arthroplasty: Preoperative Inflammatory Indices and a Novel Risk Scale (TKA-PII).Diagnostics (Basel, Switzerland) · 2026Article
- Association between systemic immune-inflammation index and ICU-acquired infection in critically Ill patients without infection: a competing risks analysis from a retrospective cohort.BMC infectious diseases · 2026Article
- Advances in the management of cancer-related incomplete intestinal obstruction: Therapeutic strategies and emerging interventions.World journal of gastroenterology · 2026Article
- Leveraging laboratory biomarkers to predict urosepsis after upper urinary tract stone surgery: an explainable machine learning approach.BMC medical informatics and decision making · 2025Article
- Evaluation of model performance in predicting sepsis after intestinal obstruction surgery: a multicenter retrospective study.Annals of medicine · 2025Article
- Comparison of systemic inflammatory markers in total knee arthroplasty under spinal vs general anesthesia: a retrospective study.BMC anesthesiology · 2025Article
- Predictive value of traditional laboratory parameters and inflammatory indices for same-day seizure recurrence in patients with epileptic seizures.Epilepsia open · 2025Article
- Association of inflammatory markers and surgical intervention with postoperative pneumonia in patients with femoral intertrochanteric fracture: A propensity score-matched cohort study.Journal of orthopaedics · 2025Article
- Preoperative SII Can Predict Postoperative Recurrence and Serious Complications in Patients with Hepatolithiasis.Journal of inflammation research · 2025Article
- Association between hematological inflammatory markers and latent TB infection: insights from NHANES 2011-2012 and transcriptomic data.Frontiers in cellular and infection microbiology · 2025Article
- Risk Factors for Postoperative Infections in Severe Traumatic Brain Injury Patients Undergoing Emergency Craniotomy.Therapeutics and clinical risk management · 2025Article
- Impact of preoperative inflammatory biomarkers on postoperative pneumonia and one-month pulmonary imaging changes after surgery for non-small cell lung cancer.Frontiers in oncology · 2025Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSepsis is a severe complication that results in increased morbidity and mortality after intestinal obstruction surgery. This study examined the role of preoperative systemic immune inflammation index (SII) for postoperative sepsis in intestinal obstruction patients.
methodsData on patients who underwent intestinal obstruction surgery were collected. SII was determined and separated into two groups (≤1792.19 and >1792.19) according to the optimal cut-off value of SII for postoperative sepsis. The odds ratio (OR) is calculated for the correlation between SII and postoperative sepsis. Additional analyses were used to estimate the robustness of SII.
resultsA total of 371 intestinal obstruction patients undergoing surgery were included in the final cohort, and 60 (16.17%) patients developed postoperative sepsis. Patients with an SII ＞1792.19 had a significantly higher risk for developing postoperative sepsis after multivariable adjustment [adjusted odds ratio = 2.12, 95% confidence interval: [1.02-4.40]]. The analysis of interaction showed no correlation between the preoperative SII and postoperative sepsis regarding age, hypertension, American Society of Anesthesiologists classification, blood loss, albumin, hemoglobin, creatinine, and leukocyte (all interactions p > .05). In subgroup analysis, all statistically significant subgroups showed that SII was a risk factor for postoperative sepsis (all p < .05). The analyses of subgroups and interactions revealed that the interaction effect of a preoperative SII ＞1792.19 and postoperative sepsis remained significant. A sensitivity analysis confirmed the robustness of the results.
conclusionsA preoperative SII ＞ 1792.19 was a risk factor for postoperative sepsis in patients undergoing intestinal obstruction surgery.
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