Evidence map›Paper›PMID 38353365›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2024

The Prevalence of Sentinel Central Events (SCent) During Drug-Induced Sleep Endoscopy.

Julianna G Rodin, Manan H Parekh, Yi Cai, Brendan T Keenan, Eric R Thuler, Everett Seay, Joshua H Atkins, Alan R Schwartz, Raj C Dedhia

Open access · greenAbstract read
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Drug-induced sleep endoscopy in obstructive sleep apnea: a systematic review and meta-analysis of sedative agents, monitoring methods, and administration techniques.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Pooled it
  2. [Dynamic assessment of upper airway in obstructive sleep apnea patients with a focus on drug-induced sleep endoscopy].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Review
  3. Ascending and Descending Pharyngeal Opening Pressures During Drug-Induced Sleep Endoscopy: Mechanistic Insights for Sleep Surgeons.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Julianna G RodinDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-7391-5020
Manan H ParekhDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yi CaiDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Brendan T KeenanDivision of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Eric R ThulerDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Everett SeayDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Joshua H AtkinsDepartment of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Alan R SchwartzDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Raj C DedhiaDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · US

Funding

Lingual muscle control of upper airway patency in obstructive sleep apneaR01HL144859 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DEDHIA, RAJ C., SCHWARTZ, ALAN R. · 2019 to 2023
$3.9M
NHLBI NIH HHS R01 HL144859
6 · The paper itself

Abstract

objectiveWith the recent addition of airflow and respiratory effort channels, our group has observed central and mixed apnea events during drug-induced sleep endoscopy (DISE). We measured the frequency and timing of sentinel central and/or mixed events (SCents), as well as assessed for differences in velum, oropharynx, tongue, and epiglottis (VOTE) classification compared to obstructive events. STUDY

designProspective single-cohort study.

settingTertiary Care Academic Medical Center.

methodsPatients underwent DISE between June 2020 and November 2022. Nasal airflow, thoracoabdominal effort belt signals, and videoendoscopy were simultaneously captured. Demographics, sleep study, and DISE data were compared among patients with and without SCents using Student's T tests or χ

resultsOn average, the cohort (n = 103) was middle-aged (53.5 ± 12.1 years), overweight (body mass index of 29.7 ± 5.3 kg/m

conclusionCentral events were present in almost half of our cohort. At least 95% of patients were expected to transition to obstructive events within 12 to 13 minutes of propofol initiation. In addition, over half of patients demonstrate significantly different VOTE scores between central and obstructive events. These factors should raise awareness of central events and scoring passive apneas during DISE and consider delaying VOTE scoring.

Indexed as

EndoscopySleep Apnea, ObstructiveAdultFemaleHumansMaleMiddle AgedPolysomnographyPrevalenceProspective StudiesSleepcentral sleep apneadrug‐induced sleep endoscopyobstructive sleep apnea

Identifiers

PMID38353365
PMCPMC11058020
OpenAlexW4391822829

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.