Evidence map›Paper›PMID 38353360›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2024

Revisiting Feeding Tube Utilization in Oropharynx Cancer: 6-Year Prospective Registry Analysis.

Brady J Anderson, Amy C Moreno, Yun Qing, J Jack Lee, Faye M Johnson, Miriam N Lango, Carly E A Barbon, Lavanya Tripuraneni, Ariana Sahli, Vicki Piper and 5 more

Open access · greenAbstract read
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Prehabilitation in Head and Neck Surgery and Reconstruction.Plastic and reconstructive surgery. Global open · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Brady J AndersonDepartment of Otolaryngology, University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-6955-797X
Amy C MorenoDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0001-6762-6807
Yun QingDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
J Jack LeeDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Faye M JohnsonDepartment of Thoracic-Head & Neck, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-2862-4160
Miriam N LangoDepartment of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-0736-7473
Carly E A BarbonSection of Speech Pathology & Audiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0001-8971-6870
Lavanya TripuraneniDepartment of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Ariana SahliDepartment of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Vicki PiperDepartment of Clinical Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Neil GrossDepartment of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-9427-0743
Clifton D FullerDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-5264-3994
Stephen Y LaiDepartment of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0001-8301-7286
Jeffrey N MyersDepartment of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Katherine A HutchesonDepartment of Head & Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-3710-5706
The University of Texas MD Anderson Cancer Center · USUniversity of Iowa · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Provider and Patient-generated Remote Oro-Dental Health Electronic Data Capture for Algorithmic Longitudinal Evaluation and Risk-Assessment (PROHEALER)K01DE030524 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MORENO, AMY CATHERINE · 2022 to 2024
$479k
NCI NIH HHS P30 CA016672NIDCR NIH HHS K01 DE030524
6 · The paper itself

Abstract

objectivePatients treated for oropharyngeal cancer (OPC) have historically demonstrated high feeding tube rates for decreased oral intake and malnutrition. We re-examined feeding tube practices in these patients. STUDY

designRetrospective analysis of prospective cohort from 2015 to 2021.

settingSingle-institution NCI-Designated Comprehensive Cancer Center.

methodsWith IRB approval, patients with new oropharyngeal squamous cell cancer or (unknown primary with neck metastasis) were enrolled. Baseline swallowing was assessed via videofluoroscopy and Performance Status Scale for Head and Neck Cancer (PSSHN). G-tubes or nasogastric tubes (NGT) were placed for weight loss before, during, or after treatment. Prophylactic NGT were placed during transoral robotic surgery (TORS). Tube duration was censored at last disease-free follow-up. Multivariate regression was performed for G-tube placement (odds ratio [OR] [95% confidence interval [CI]) and removal (Cox hazard ratio, hazard ratio [HR] [95% CI]).

resultsOf 924 patients, most had stage I to II (81%), p16+ (89%), node-positive (88%) disease. Median follow-up was 2.6 years (interquartile range 1.5-3.9). Most (91%) received radiation/chemoradiation, and 16% received TORS. G-tube rate was 27% (5% after TORS). G-tube risk was increased with chemoradiation (OR 2.78 [1.87-4.22]) and decreased with TORS (OR 0.31 [0.15-0.57]) and PSSHN-Diet score ≥60 (OR 0.26 [0.15-0.45]). G-tube removal probability over time was lower for T3 to T4 tumors (HR 0.52 [0.38-0.71]) and higher for PSSHN-Diet score ≥60 (HR 1.65 [1.03-2.66]).

conclusionsIn this modern cohort of patients treated for OPC, 27% received G-tubes-50% less than institutional rates 10 years ago. Patients with preserved baseline swallowing and/or those eligible for TORS may have lower G-tube risk and duration.

Indexed as

Enteral NutritionIntubation, GastrointestinalOropharyngeal NeoplasmsRegistriesAgedFemaleHumansMaleMiddle AgedProspective StudiesRetrospective StudiesRobotic Surgical Procedureschemoradiationfeeding tubegastrostomyG‐tubenasogastricoropharyngeal cancer (OPC)radiationtransoral robotic surgery (TORS)

Identifiers

PMID38353360
PMCPMC11225069
OpenAlexW4391822884

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.