Evidence map›Paper›PMID 38352833›Full record

ArticleACS medicinal chemistry letters2024

Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress.

Jesse Gordon-Blake, Kiira Ratia, Victoria Weidig, Ganga Reddy Velma, Martha Ackerman-Berrier, Christopher Penton, Soumya Reddy Musku, Erick T M Alves, Tom Driver, Leon Tai and 1 more

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jesse Gordon-BlakeDepartment of Pharmaceutical Sciences, Research Resources Center, Department of Chemistry, and Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID https://orcid.org/0000-0001-8077-1240
Kiira RatiaDepartment of Pharmaceutical Sciences, Research Resources Center, Department of Chemistry, and Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Victoria WeidigDepartment of Pharmaceutical Sciences, Research Resources Center, Department of Chemistry, and Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Ganga Reddy VelmaDepartment of Pharmacology & Toxicology, R Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.ORCID https://orcid.org/0000-0001-5054-2519
Martha Ackerman-BerrierDepartment of Pharmacology & Toxicology, R Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.
Christopher PentonDepartment of Pharmacology & Toxicology, R Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.
Soumya Reddy MuskuDepartment of Pharmacology & Toxicology, R Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.
Erick T M AlvesDepartment of Pharmacology & Toxicology, R Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.
Tom DriverDepartment of Pharmaceutical Sciences, Research Resources Center, Department of Chemistry, and Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID https://orcid.org/0000-0001-7001-342X
Leon TaiDepartment of Pharmaceutical Sciences, Research Resources Center, Department of Chemistry, and Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Gregory R J ThatcherDepartment of Pharmacology & Toxicology, R Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.ORCID https://orcid.org/0000-0002-7757-1739
University of Arizona · USUniversity of Illinois Chicago · US

Funding

Novel allosteric activation of nicotinamide rescueRF1AG067771 · NIA · UNIVERSITY OF ARIZONA · PI THATCHER, GREGORY R. J · 2020 to 2020
$2.3M
NIA NIH HHS RF1 AG067771
6 · The paper itself

Abstract

Evidence supports boosting nicotinamide adenine dinucleotide (NAD

Identifiers

PMID38352833
PMCPMC10860701
OpenAlexW4391187887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.