Evidence map›Paper›PMID 38352654›Full record

ReviewFrontiers in psychiatry2024

Understanding the role of AMPA receptors in autism: insights from circuit and synapse dysfunction.

Andres Jimenez-Gomez, Megan X Nguyen, Jason S Gill

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Andres Jimenez-GomezNeurodevelopmental Disabilities Program, Department of Neurology, Joe DiMaggio Children's Hospital, Hollywood, FL, United States.
Megan X NguyenDepartment of Pediatrics, Division of Neurology & Developmental Neurosciences, Baylor College of Medicine, Houston, TX, United States.
Jason S GillDepartment of Pediatrics, Division of Neurology & Developmental Neurosciences, Baylor College of Medicine, Houston, TX, United States.
Joe DiMaggio Children's Hospital · USNeurological Research Institute · USTexas Children's Hospital · US

Funding

Unraveling the Dynamic Role of Purkinje Cell Neurotransmission in Neurodevelopment.K08NS121600 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI GILL, JASON SINGH · 2021 to 2025
$956k
NINDS NIH HHS K08 NS121600
6 · The paper itself

Abstract

Autism spectrum disorders represent a diverse etiological spectrum that converge on a syndrome characterized by discrepant deficits in developmental domains often highlighted by concerns in socialization, sensory integration, and autonomic functioning. Importantly, the incidence and prevalence of autism spectrum disorders have seen sharp increases since the syndrome was first described in the 1940s. The wide etiological spectrum and rising number of individuals being diagnosed with the condition lend urgency to capturing a more nuanced understanding of the pathogenic mechanisms underlying the autism spectrum disorders. The current review seeks to understand how the disruption of AMPA receptor (AMPAr)-mediated neurotransmission in the cerebro-cerebellar circuit, particularly in genetic autism related to SHANK3 or SYNGAP1 protein dysfunction function and autism associated with

Indexed as

AMPAASDautismcerebro-cerebellarcircuitsSHANK3synaptopathySynGAP1

Identifiers

PMID38352654
PMCPMC10861716
OpenAlexW4391359045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.