Evidence map›Paper›PMID 38352614›Full record

ArticlebioRxiv : the preprint server for biology2024

Global MEG Resting State Functional Connectivity in Children with Autism and Sensory Processing Dysfunction.

Carly Demopoulos, Xuan Jesson, Molly Rae Gerdes, Barbora G Jurigova, Leighton B Hinkley, Kamalini G Ranasinghe, Shivani Desai, Susanne Honma, Danielle Mizuiri, Anne Findlay and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Carly DemopoulosDepartment of Psychiatry, University of California San Francisco, 675 18 Street, San Francisco, CA 94107.ORCID 0000-0003-2082-3947
Xuan JessonDepartment of Psychology, Palo Alto University, 1791 Arastradero Road, Palo Alto, CA 94304.
Molly Rae GerdesCortica Healthcare, Department of Neurodevelopmental Medicine, 4000 Civic Center Drive, San Rafael, CA 94903.
Barbora G JurigovaCortica Healthcare, Department of Neurodevelopmental Medicine, 4000 Civic Center Drive, San Rafael, CA 94903.
Leighton B HinkleyDepartment of Radiology & Biomedical Imaging, University of California-San Francisco, 513 Parnassus Avenue, S362, San Francisco, CA 94143.
Kamalini G RanasingheUniversity of California-San Francisco, Department of Neurology, 675 Nelson Rising Lane, San Francisco, CA 94143.
Shivani DesaiUniversity of California-San Francisco, Department of Neurology, 675 Nelson Rising Lane, San Francisco, CA 94143.
Susanne HonmaDepartment of Radiology & Biomedical Imaging, University of California-San Francisco, 513 Parnassus Avenue, S362, San Francisco, CA 94143.
Danielle MizuiriDepartment of Radiology & Biomedical Imaging, University of California-San Francisco, 513 Parnassus Avenue, S362, San Francisco, CA 94143.
Anne FindlayDepartment of Radiology & Biomedical Imaging, University of California-San Francisco, 513 Parnassus Avenue, S362, San Francisco, CA 94143.
Srikantan S NagarajanDepartment of Radiology & Biomedical Imaging, University of California-San Francisco, 513 Parnassus Avenue, S362, San Francisco, CA 94143.
Elysa J MarcoCortica Healthcare, Department of Neurodevelopmental Medicine, 4000 Civic Center Drive, San Rafael, CA 94903.ORCID 0000-0002-5284-9888
University of California, San Francisco · USNeuroDevelopment Center · USPalo Alto University · US

Funding

The role of the cerebellum in speechR01DC017091 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI John Francis Houde, RICHARD IVRY · 2019 to 2026
$4.5M
Neural mechanisms of speech motor control in Autism Spectrum DisordersR01DC019167 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DEMOPOULOS, CARLY, LI, YAN · 2021 to 2025
$4.2M
Dynamic Brain Imaging of Speech in Primary Progressive AphasiaR01NS100440 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARIA LUISA GORNO TEMPINI, John Francis Houde · 2017 to 2026
$3.6M
Network Modelling of Multimodal Dynamics in Alzheimer’s Disease and DementiaRF1AG062196 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAGARAJAN, SRIKANTAN S., RAJ, ASHISH · 2019 to 2019
$3.0M
Vocal sensorimotor control and voice abnormalities in Autism Spectrum DisordersK23DC016637 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DEMOPOULOS, CARLY · 2018 to 2022
$1.0M
Magnetic Source Imaging and Sensory Behavioral Characterization in AutismK23MH083890 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARCO, ELYSA JILL · 2008 to 2011
$695k
NIA NIH HHS RF1 AG062196NIDCD NIH HHS K23 DC016637NIDCD NIH HHS R01 DC017091NIDCD NIH HHS R01 DC019167NIMH NIH HHS K23 MH083890NINDS NIH HHS R01 NS100440
6 · The paper itself

Abstract

Sensory processing dysfunction not only affects most individuals with autism spectrum disorder (ASD), but at least 5% of children without ASD also experience dysfunctional sensory processing. Our understanding of the relationship between sensory dysfunction and resting state brain activity is still emerging. This study compared long-range resting state functional connectivity of neural oscillatory behavior in children aged 8-12 years with autism spectrum disorder (ASD; N=18), those with sensory processing dysfunction (SPD; N=18) who do not meet ASD criteria, and typically developing control participants (TDC; N=24) using magnetoencephalography (MEG). Functional connectivity analyses were performed in the alpha and beta frequency bands, which are known to be implicated in sensory information processing. Group differences in functional connectivity and associations between sensory abilities and functional connectivity were examined. Distinct patterns of functional connectivity differences between ASD and SPD groups were found only in the beta band, but not in the alpha band. In both alpha and beta bands, ASD and SPD cohorts differed from the TDC cohort. Somatosensory cortical beta-band functional connectivity was associated with tactile processing abilities, while higher-order auditory cortical alpha-band functional connectivity was associated with auditory processing abilities. These findings demonstrate distinct long-range neural synchrony alterations in SPD and ASD that are associated with sensory processing abilities. Neural synchrony measures could serve as potential sensitive biomarkers for ASD and SPD.

Identifiers

PMID38352614
PMCPMC10862722
OpenAlexW4391303205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.