Evidence map›Paper›PMID 38352566›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Clinical and epidemiological characteristics of Madariaga and Venezuelan equine encephalitis virus infections.

Luis Felipe Rivera, Carlos Lezcano-Coba, Josefrancisco Galué, Xacdiel Rodriguez, Yelissa Juarez, William M de Souza, Zeuz Capitan-Barrios, Anayansi Valderrama, Leyda Abrego, Hector Cedeño and 15 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 9 institutions in 5 countries.

Luis Felipe RiveraInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
Carlos Lezcano-CobaInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
Josefrancisco GaluéInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
Xacdiel RodriguezInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
Yelissa JuarezInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
William M de SouzaUniversity of Kentucky, College of Medicine, Lexington, Kentucky, USA.
Zeuz Capitan-BarriosCarson Centre for Research in Environment and Emerging Infectious Diseases, La Peñita, Darién, Panama.
Anayansi ValderramaInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
Leyda AbregoInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
Hector CedeñoMinistry of Health, Panama City, Panama.
Carmela JackmanMinistry of Health, Panama City, Panama.
Jesse J WaggonerEmory University, Atlanta, Georgia, USA.
Patricia V AguilarThe University of Texas Medical Branch, Galveston, TX, USA.
Hilda GuzmanThe University of Texas Medical Branch, Galveston, TX, USA.
Scott C WeaverThe University of Texas Medical Branch, Galveston, TX, USA.
Robert B TeshThe University of Texas Medical Branch, Galveston, TX, USA.
Sandra López-VèrgesInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
Christl A DonnellyUniversity of Oxford, Oxford, United Kingdom.ORCID 0000-0002-0195-2463
Cassia F EstofoleteFaculdade de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo Brazil.
Mauricio L NogueiraThe University of Texas Medical Branch, Galveston, TX, USA.
Nuno R FariaImperial College London, London, United Kingdom.
Nikos VasilakisThe University of Texas Medical Branch, Galveston, TX, USA.
Amy Y VittorUniversity of Florida, Gainesville, Florida, USA.
Darci R SmithNaval Medical Research Command, Ft. Detrick, MD, USA.
Jean-Paul CarreraInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama.
Instituto Conmemorativo Gorgas de Estudios de la Salud · PAThe University of Texas Medical Branch at Galveston · USFaculdade de Medicina de São José do Rio Preto · BRUniversidad de Panamá · PAUniversity of Florida · USEmory University · USHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversity of Kentucky · USUniversity of Oxford · GB

Funding

Coordinating Research on Emerging Arboviral Threats Encompassing the Neotropics II (CREATE-NEO II)U01AI151807 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kathryn Alyce Hanley, MAURICIO Lacerda NOGUEIRA · 2020 to 2026
$9.8M
World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)R24AI120942 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WEAVER, SCOTT C · 2016 to 2024
$8.5M
Once Bitten: Detecting the World???s Most Common Vector-Borne PathogensK08AI110528 · NIAID · STANFORD UNIVERSITY · PI WAGGONER, JESSE · 2014 to 2018
$917k
Medical Research Council MR/S019510/1NIAID NIH HHS K08 AI110528NIAID NIH HHS R24 AI120942NIAID NIH HHS U01 AI151807Wellcome Trust
6 · The paper itself

Abstract

Madariaga virus (MADV) and Venezuelan equine encephalitis virus (VEEV) are emerging arboviruses affecting rural and remote areas of Latin America. However, there are limited clinical and epidemiological reports available, and outbreaks are occurring at an increasing frequency. We addressed this gap by analyzing all the available clinical and epidemiological data of MADV and VEEV infections recorded since 1961 in Panama. A total of 168 of human alphavirus encephalitis cases were detected in Panama from 1961 to 2023. Here we describe the clinical signs and symptoms and epidemiological characteristics of these cases, and also explored signs and symptoms as potential predictors of encephalitic alphavirus infection when compared to those of other arbovirus infections occurring in the region. Our results highlight the challenges clinical diagnosis of alphavirus disease in endemic regions with overlapping circulation of multiple arboviruses.

Indexed as

alphavirusesMadariaga Virusoutbreak investigationVenezuelan equine encephalitis

Identifiers

PMID38352566
PMCPMC10863014
OpenAlexW4391520669

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.