Evidence map›Paper›PMID 38352559›Full record

ArticlebioRxiv : the preprint server for biology2024

Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a

Hassan Bukhari, Vanitha Nithianandam, Rachel A Battaglia, Anthony Cicalo, Souvarish Sarkar, Aram Comjean, Yanhui Hu, Matthew J Leventhal, Xianjun Dong, Mel B Feany

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hassan BukhariDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Vanitha NithianandamDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Rachel A BattagliaDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Anthony CicaloAligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815.
Souvarish SarkarDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Aram ComjeanDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Yanhui HuDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Matthew J LeventhalDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
Xianjun DongAligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815.
Mel B FeanyDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.ORCID 0000-0003-0315-7970
Brigham and Women's Hospital · USHarvard University · USMassachusetts Institute of Technology · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Integrative Multi-Omic Discovery of Proximal Mechanisms Driving Age-Dependent NeurodegenerationRF1AG057331 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI FEANY, MEL B, FRAENKEL, ERNEST · 2017 to 2017
$4.8M
Functional analysis of glia in tauopathyRF1AG076214 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI FEANY, MEL B, FRAENKEL, ERNEST · 2022 to 2025
$4.1M
NIA NIH HHS RF1 AG057331NIA NIH HHS RF1 AG076214NIH HHS P40 OD018537
6 · The paper itself

Abstract

Missense mutations in the gene encoding the microtubule-associated protein tau cause autosomal dominant forms of frontotemporal dementia. Multiple models of frontotemporal dementia based on transgenic expression of human tau in experimental model organisms, including

Identifiers

PMID38352559
PMCPMC10862891
OpenAlexW4391518886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.