Evidence map›Paper›PMID 38352558›Full record

ArticlebioRxiv : the preprint server for biology2024

Structural Basis for Oxidized Glutathione Recognition by the Yeast Cadmium Factor 1.

Tik Hang Soong, Clare Hotze, Nitesh Kumar Khandelwal, Thomas M Tomasiak

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tik Hang SoongDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA.
Clare HotzeDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA.
Nitesh Kumar KhandelwalDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA.
Thomas M TomasiakDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA.
University of Arizona · US

Funding

ATP Binding Cassette (ABC) Transporters in Fungal Drug ToleranceR01AI156270 · NIAID · UNIVERSITY OF ARIZONA · PI TOMASIAK, THOMAS MICHAEL · 2021 to 2025
$1.9M
NIAID NIH HHS R01 AI156270
6 · The paper itself

Abstract

Transporters from the ABCC family have an essential role in detoxifying electrophilic compounds including metals, drugs, and lipids, often through conjugation with glutathione complexes. The Yeast Cadmium Factor 1 (Ycf1) transports glutathione alone as well as glutathione conjugated to toxic heavy metals including Cd

Indexed as

ABC transporterBiochemistryBiological Sciencesglutathione-metal conjugationglutathione transporter

Identifiers

PMID38352558
PMCPMC10862839
OpenAlexW4391444840

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.