Evidence map›Paper›PMID 38352555›Full record

ArticlebioRxiv : the preprint server for biology2024

Harnessing the regenerative potential of

Kwangdeok Shin, Anjelica Rodriguez-Parks, Chanul Kim, Isabella M Silaban, Yu Xia, Jisheng Sun, Chenyang Dong, Sunduz Keles, Jinhu Wang, Jingli Cao and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kwangdeok ShinDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, 53705, USA.
Anjelica Rodriguez-ParksDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, 53705, USA.
Chanul KimDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, 53705, USA.
Isabella M SilabanDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, 53705, USA.
Yu XiaCardiovascular Research Institute, Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, 10065, USA.
Jisheng SunCardiology Division, School of Medicine, Emory University, Atlanta, GA 30322, USA.
Chenyang DongDepartments of Statistics and of Biostatistics and Medical Informatics, University of Wisconsin - Madison, Madison, WI 53706, USA.
Sunduz KelesDepartments of Statistics and of Biostatistics and Medical Informatics, University of Wisconsin - Madison, Madison, WI 53706, USA.
Jinhu WangCardiology Division, School of Medicine, Emory University, Atlanta, GA 30322, USA.
Jingli CaoCardiovascular Research Institute, Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, 10065, USA.
Junsu KangDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI, 53705, USA.
University of Wisconsin–Madison · USCornell University · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
Molecular and Genetic Analysis of Fin Regeneration in ZebrafishR35GM137878 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Junsu Kang · 2020 to 2026
$3.1M
Mechanisms controlling epicardial-dependent promotion of heart regeneration in zebrafish.R01HL155607 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jingli Cao · 2021 to 2026
$2.9M
Spatiotemporal regulation of polyploidy in zebrafish cardiac tissue regenerationR01HL166518 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jingli Cao · 2023 to 2026
$2.8M
Dissecting injury-responsive gene expression during zebrafish heart regenerationR01HL151522 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Junsu Kang · 2021 to 2026
$2.6M
Characterization of hapln1a positive cells during zebrafish heart regenerationR01HL142762 · NHLBI · EMORY UNIVERSITY · PI Jinhu Wang · 2019 to 2026
$2.6M
NCI NIH HHS P30 CA014520NHLBI NIH HHS R01 HL142762NHLBI NIH HHS R01 HL151522NHLBI NIH HHS R01 HL155607NHLBI NIH HHS R01 HL166518NIGMS NIH HHS R35 GM137878
6 · The paper itself

Abstract

Balancing between regenerative processes and fibrosis is crucial for heart repair, yet strategies regulating this balance remain a barrier to developing therapies. While Interleukin11 (IL11) is known as a fibrotic factor, its contribution to heart regeneration is poorly understood. We uncovered that

Identifiers

PMID38352555
PMCPMC10862709
OpenAlexW4391396378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.